OBJECTIVE: To study the association of peripheral blood pH early after birth with amplitude-integrated electroencephalography (aEEG) findings in neonates with intrauterine distress. METHODS: The clinical data of the neonates with intrauterine distress who were born from January 2017 to May 2018 were collected. According to peripheral blood pH within 30 minutes after birth, these neonates were divided into 3 groups: pH ≤7.15, 7.15 <pH ≤7.25 and pH >7.25, with 30 neonates in each group. aEEG mornitoring was performed within 6 hours after birth, and the abnormal rate of aEEG findings and average cerebral function monitoring (CFM) score were compared between groups. RESULTS: The pH ≤7.15 group had a significantly higher abnormal rate of aEEG findings than the pH >7.25 group (P<0.0167) and a significantly lower aEEG CFM score than the 7.15 <pH ≤7.25 and pH >7.25 groups (P<0.05). Peripheral blood pH was positively correlated with the CFM score (r=0.26, P<0.05). CONCLUSIONS: Peripheral blood pH is significantly associated with aEEG findings in neonates with intrauterine distress. Active measures should be adopted for the prevention and treatment of nervous system injury in neonates with intrauterine distress who have a significant reduction in peripheral blood pH early after birth (pH ≤7.15).
OBJECTIVE: To study the association of peripheral blood pH early after birth with amplitude-integrated electroencephalography (aEEG) findings in neonates with intrauterine distress. METHODS: The clinical data of the neonates with intrauterine distress who were born from January 2017 to May 2018 were collected. According to peripheral blood pH within 30 minutes after birth, these neonates were divided into 3 groups: pH ≤7.15, 7.15 <pH ≤7.25 and pH >7.25, with 30 neonates in each group. aEEG mornitoring was performed within 6 hours after birth, and the abnormal rate of aEEG findings and average cerebral function monitoring (CFM) score were compared between groups. RESULTS: The pH ≤7.15 group had a significantly higher abnormal rate of aEEG findings than the pH >7.25 group (P<0.0167) and a significantly lower aEEG CFM score than the 7.15 <pH ≤7.25 and pH >7.25 groups (P<0.05). Peripheral blood pH was positively correlated with the CFM score (r=0.26, P<0.05). CONCLUSIONS: Peripheral blood pH is significantly associated with aEEG findings in neonates with intrauterine distress. Active measures should be adopted for the prevention and treatment of nervous system injury in neonates with intrauterine distress who have a significant reduction in peripheral blood pH early after birth (pH ≤7.15).