Literature DB >> 31103770

Can the Etiopathogenesis of Chiari Malformation Be Craniocervical Junction Stabilization Difference? Morphometric Analysis of Craniocervical Junction Ligaments.

Burak Karaaslan1, Alp Özgün Börcek2, Murat Uçar3, Şükrü Aykol2.   

Abstract

OBJECTIVE: The craniocervical junction permits a certain amount of mobility for the cervical spine. The biomechanical properties of occipital bone-atlas joint mainly depend on the bony structure, and atlas-axis joint biomechanical properties mainly depend on ligamentous structure. The underlying etiologic factor of Chiari malformation (CM) is debatable. Nowadays, some researchers argue that stabilization difference is one of the suspicious factors for etiopathogenesis. We aim to analyze the ligamentous morphometric differences of CM.
METHODS: Magnetic resonance images of 93 adult healthy subjects (n = 93) without any craniocervical junction development abnormalities and 25 (n = 25) adult patients with craniocervical junction development abnormalities (Arnold CM) were evaluated. Length, width, and length-width ratios of ligaments were evaluated.
RESULTS: Length of transverse ligament (mean: 23 ± 3.6 [range: 12.1-31.4]) in the normal population was significantly longer than transverse ligament length in CM patients (mean: 21.3 ± 2.5 [range: 17.2-24.9]). Length of alar ligament (mean: 10.7 ± 2 [range: 5.1-15.4]) in the normal population was significantly longer than alar ligament length in CM patients (mean: 8.8 ± 3.8 [range: 1.1-16.6]) (P = 0.007).
CONCLUSIONS: Craniocervical ligaments play an important role in maintaining stability and motion capacity of this region. This study promoted better understanding of craniocervical junction anomalies and provided data that facilitate performing more precise surgical treatment.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Chiari malformation; Craniocervical ligaments; Foramen magnum decompression

Mesh:

Year:  2019        PMID: 31103770     DOI: 10.1016/j.wneu.2019.05.072

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  3 in total

Review 1.  Is there a morphometric cause of Chiari malformation type I? Analysis of existing literature.

Authors:  William H Shuman; Aislyn DiRisio; Alejandro Carrasquilla; Colin D Lamb; Addison Quinones; Aymeric Pionteck; Yang Yang; Mehmet Kurt; Raj K Shrivastava
Journal:  Neurosurg Rev       Date:  2021-07-13       Impact factor: 3.042

2.  A new hypothesis for the pathophysiology of symptomatic adult Chiari malformation Type I.

Authors:  Rick Labuda; Blaise Simplice Talla Nwotchouang; Alaaddin Ibrahimy; Philip A Allen; John N Oshinski; Petra Klinge; Francis Loth
Journal:  Med Hypotheses       Date:  2021-12-14       Impact factor: 1.538

3.  Occipital condyle screw fixation after posterior decompression for Chiari malformation: Technical report and application.

Authors:  Arpan R Chakraborty; Panayiotis E Pelargos; Camille K Milton; Michael D Martin; Andrew M Bauer; Ian F Dunn
Journal:  Surg Neurol Int       Date:  2021-11-02
  3 in total

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