Literature DB >> 3110356

Independent association of T cell receptor beta and gamma chains with CD3 in the same cell.

F Koning, W L Maloy, D Cohen, J E Coligan.   

Abstract

We have demonstrated that the PEER cell line, which expresses a CD3-associated TCR gamma chain on the cell surface, synthesizes TCR beta chain intracellularly. A percentage of this TCR beta chain associates with the CD3 complex intracellularly. These results indicate that TCR beta and gamma chains can be synthesized by one cell line, and that these chains can independently associate with the CD3 complex. However, the results argue against the formation of TCR beta gamma chain complexes in this cell line.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3110356      PMCID： PMC2189592          DOI： 10.1084/jem.166.2.595

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  15 in total

Review 1.  The antigen-specific, major histocompatibility complex-restricted receptor on T cells.

Authors:  P Marrack; J Kappler
Journal:  Adv Immunol       Date:  1986       Impact factor: 3.543

2.  Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex.

Authors:  A J Furley; S Mizutani; K Weilbaecher; H S Dhaliwal; A M Ford; L C Chan; H V Molgaard; B Toyonaga; T Mak; P van den Elsen
Journal:  Cell       Date:  1986-07-04       Impact factor: 41.582

3.  Expression of T3 in association with a molecule distinct from the T-cell antigen receptor heterodimer.

Authors:  A Weiss; M Newton; D Crommie
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

4.  Diversity and structure of human T-cell receptor beta-chain variable region genes.

Authors:  P Concannon; L A Pickering; P Kung; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

5.  A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes.

Authors:  I Bank; R A DePinho; M B Brenner; J Cassimeris; F W Alt; L Chess
Journal:  Nature       Date:  1986 Jul 10-16       Impact factor: 49.962

Review 6.  A review of the structure and function of the T-cell receptor-T3 complex.

Authors:  H C Oettgen; C Terhorst
Journal:  Crit Rev Immunol       Date:  1987       Impact factor: 2.214

7.  Identification of a putative second T-cell receptor.

Authors:  M B Brenner; J McLean; D P Dialynas; J L Strominger; J A Smith; F L Owen; J G Seidman; S Ip; F Rosen; M S Krangel
Journal:  Nature       Date:  1986 Jul 10-16       Impact factor: 49.962

8.  Cross-linking of human T cell receptor proteins: association between the T cell idiotype beta subunit and the T3 glycoprotein heavy subunit.

Authors:  M B Brenner; I S Trowbridge; J L Strominger
Journal:  Cell       Date:  1985-01       Impact factor: 41.582

9.  Expression of T-cell antigen receptor genes during fetal development in the thymus.

Authors:  H R Snodgrass; Z Dembić; M Steinmetz; H von Boehmer
Journal:  Nature       Date:  1985 May 16-22       Impact factor: 49.962

10.  Rearrangement and expression of the alpha, beta, and gamma chain T cell receptor genes in human thymic leukemia cells and functional T cells.

Authors:  R N Sangster; J Minowada; N Suciu-Foca; M Minden; T W Mak
Journal:  J Exp Med       Date:  1986-06-01       Impact factor: 14.307
View more
  11 in total

Review 1.  Newly identified gamma delta and beta delta T-cell receptors.

Authors:  F Hochstenbach; M B Brenner
Journal:  J Clin Immunol       Date:  1990-01       Impact factor: 8.317

Review 2.  Surface proteins and glycoproteins of human leucocytes.

Authors:  V Horejsí; V Bazil
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

3.  Double-negative (CD4-CD8-) lymphocytes bearing T-cell receptor alpha and beta chains in normal human skin.

Authors:  V Groh; M Fabbi; F Hochstenbach; R T Maziarz; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

4.  Human epidermal T cells predominantly belong to the lineage expressing alpha/beta T cell receptor.

Authors:  C A Foster; H Yokozeki; K Rappersberger; F Koning; B Volc-Platzer; A Rieger; J E Coligan; K Wolff; G Stingl
Journal:  J Exp Med       Date:  1990-04-01       Impact factor: 14.307

5.  TCRγ4δ1-engineered αβT cells exhibit effective antitumor activity.

Authors:  Kangxia He; Hongqin You; Yuxia Li; Lianxian Cui; Jianmin Zhang; Wei He
Journal:  Mol Med       Date:  2016-07-26       Impact factor: 6.354

6.  Complex rearrangements within the human J delta-C delta/J alpha-C alpha locus and aberrant recombination between J alpha segments.

Authors:  R Baer; T Boehm; H Yssel; H Spits; T H Rabbitts
Journal:  EMBO J       Date:  1988-06       Impact factor: 11.598

7.  Surface expression of only gamma delta and/or alpha beta T cell receptor heterodimers by cells with four (alpha, beta, gamma, delta) functional receptor chains.

Authors:  T Saito; F Hochstenbach; S Marusic-Galesic; A M Kruisbeek; M Brenner; R N Germain
Journal:  J Exp Med       Date:  1988-09-01       Impact factor: 14.307

8.  RNA-transfection of γ/δ T cells with a chimeric antigen receptor or an α/β T-cell receptor: a safer alternative to genetically engineered α/β T cells for the immunotherapy of melanoma.

Authors:  Dennis C Harrer; Bianca Simon; Shin-Ichiro Fujii; Kanako Shimizu; Ugur Uslu; Gerold Schuler; Kerstin F Gerer; Stefanie Hoyer; Jan Dörrie; Niels Schaft
Journal:  BMC Cancer       Date:  2017-08-17       Impact factor: 4.430

9.  A novel antibody-TCR (AbTCR) platform combines Fab-based antigen recognition with gamma/delta-TCR signaling to facilitate T-cell cytotoxicity with low cytokine release.

Authors:  Yiyang Xu; Zhiyuan Yang; Lucas H Horan; Pengbo Zhang; Lianxing Liu; Bryan Zimdahl; Shon Green; Jingwei Lu; Javier F Morales; David M Barrett; Stephan A Grupp; Vivien W Chan; Hong Liu; Cheng Liu
Journal:  Cell Discov       Date:  2018-11-20       Impact factor: 10.849

10.  Human adenovirus-specific γ/δ and CD8+ T cells generated by T-cell receptor transfection to treat adenovirus infection after allogeneic stem cell transplantation.

Authors:  Jan Dörrie; Christian Krug; Christian Hofmann; Ina Müller; Verena Wellner; Ilka Knippertz; Stephan Schierer; Simone Thomas; Elke Zipperer; Dieter Printz; Gerhard Fritsch; Gerold Schuler; Niels Schaft; Rene Geyeregger
Journal:  PLoS One       Date:  2014-10-07       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.