Literature DB >> 31102471

A very potent factor V inhibitor interferes with the levels of all coagulation factors and causes a fatal hemorrhagic syndrome.

Claire Hoffmann1, Jean Amiral2, Schéhérazade Rezig3, Hélène Kerspern4, Hélène Jantzem5, Sara Robin6, Adam Collins1, Clelia Mornet1, Fanny Mingant1, Brigitte Pan Petesch7, Jean-Christophe Ianotto7, Eric Lippert1,8, Hubert Galinat1.   

Abstract

We report a very high factor V inhibitor affecting the measurement of all coagulation factors besides fibrinogen, all these factors being dramatically decreased. This inhibitor could be linked to antibiotic use. The patient died of massive hemorrhage before a plasma exchange could be initiated.
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  coagulation factors; factor V inhibitor; factor inhibitor

Year:  2019        PMID： 31102471     DOI： 10.1111/ejh.13249

Source DB:  PubMed          Journal:  Eur J Haematol        ISSN： 0902-4441            Impact factor:   2.997


  1 in total

1.  An acquired factor V inhibitor induced uncontrolled bleeding in a postsurgery patient.

Authors:  Riccardo Bruna; Riccardo Moia; Alessandra Valpreda; Enrico Dosio; Roberta Rolla; Augusto Federici; Umberto Dianzani; Gianluca Gaidano; Andrea Patriarca
Journal:  Clin Case Rep       Date:  2020-12-01
  1 in total

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