Literature DB >> 31102366

[Research advances on the role of exosomes in chemotherapy resistance of ovarian cancer].

Xiameng Shen1, Weiguo Lyu1.   

Abstract

Chemotherapy resistance is one of the biggest challenges in treatment of ovarian cancer. Mounting evidence shows that the exosomes shedding from tumor cells are considered to be involved in chemotherapy resistance of ovarian cancer by enhanced exosomal export of drugs, transferring RNAs or proteins and interfering with the bioactivity of therapeutic anti-tumor antibodies. In this review, we display the correlation between exosomes and chemotherapy resistance of ovarian cancer, the mechanism of exosomes involved in chemotherapy resistance of ovarian cancer, and discuss the potential clinical values of exosomes in chemotherapy resistance of ovarian cancer.

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Year:  2019        PMID： 31102366      PMCID： PMC8800642          DOI： 10.3785/j.issn.1008-9292.2019.02.17

Source DB:  PubMed          Journal:  Zhejiang Da Xue Xue Bao Yi Xue Ban        ISSN： 1008-9292


  28 in total

1.  The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients.

Authors:  Marzia Del Re; Elisa Biasco; Stefania Crucitta; Lisa Derosa; Eleonora Rofi; Cinzia Orlandini; Mario Miccoli; Luca Galli; Alfredo Falcone; Guido W Jenster; Ron H van Schaik; Romano Danesi
Journal:  Eur Urol       Date:  2016-10-10       Impact factor: 20.096

2.  UCH-L1-containing exosomes mediate chemotherapeutic resistance transfer in breast cancer.

Authors:  Kuan Ning; Teng Wang; Xu Sun; Pengfei Zhang; Yun Chen; Jian Jin; Dong Hua
Journal:  J Surg Oncol       Date:  2017-03-23       Impact factor: 3.454

3.  Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes.

Authors:  Lydia Alvarez-Erviti; Yiqi Seow; Haifang Yin; Corinne Betts; Samira Lakhal; Matthew J A Wood
Journal:  Nat Biotechnol       Date:  2011-03-20       Impact factor: 54.908

4.  Milk-derived exosomes for oral delivery of paclitaxel.

Authors:  Ashish K Agrawal; Farrukh Aqil; Jeyaprakash Jeyabalan; Wendy A Spencer; Joshua Beck; Beth W Gachuki; Sara S Alhakeem; Karine Oben; Radha Munagala; Subbarao Bondada; Ramesh C Gupta
Journal:  Nanomedicine       Date:  2017-03-11       Impact factor: 5.307

Review 5.  Platinum versus platinum-combination chemotherapy in platinum-sensitive recurrent ovarian cancer: a meta-analysis using individual patient data.

Authors:  F A Raja; N Counsell; N Colombo; J Pfisterer; A du Bois; M K Parmar; I B Vergote; A Gonzalez-Martin; D S Alberts; M Plante; V Torri; J A Ledermann
Journal:  Ann Oncol       Date:  2013-11-04       Impact factor: 32.976

6.  Cisplatin induces the release of extracellular vesicles from ovarian cancer cells that can induce invasiveness and drug resistance in bystander cells.

Authors:  Priya Samuel; Laura Ann Mulcahy; Fiona Furlong; Helen O McCarthy; Susan Ann Brooks; Muller Fabbri; Ryan Charles Pink; David Raul Francisco Carter
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2018-01-05       Impact factor: 6.237

7.  Exosome removal as a therapeutic adjuvant in cancer.

Authors:  Annette M Marleau; Chien-Shing Chen; James A Joyce; Richard H Tullis
Journal:  J Transl Med       Date:  2012-06-27       Impact factor: 5.531

8.  Secretion of annexin A3 from ovarian cancer cells and its association with platinum resistance in ovarian cancer patients.

Authors:  Jie Yin; Xuedong Yan; Xin Yao; Yongli Zhang; Ying Shan; Ning Mao; Yili Yang; Lingya Pan
Journal:  J Cell Mol Med       Date:  2012-02       Impact factor: 5.310

9.  Increasing circulating exosomes-carrying TRPC5 predicts chemoresistance in metastatic breast cancer patients.

Authors:  Teng Wang; Kuan Ning; Ting-Xun Lu; Xu Sun; Linfang Jin; Xiaowei Qi; Jian Jin; Dong Hua
Journal:  Cancer Sci       Date:  2017-03       Impact factor: 6.716

10.  Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.

Authors:  Eduardo Reátegui; Kristan E van der Vos; Charles P Lai; Mahnaz Zeinali; Nadia A Atai; Berent Aldikacti; Frederick P Floyd; Aimal H Khankhel; Vishal Thapar; Fred H Hochberg; Lecia V Sequist; Brian V Nahed; Bob S Carter; Mehmet Toner; Leonora Balaj; David T Ting; Xandra O Breakefield; Shannon L Stott
Journal:  Nat Commun       Date:  2018-01-12       Impact factor: 14.919
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  1 in total

1.  Circulating exosomal circFoxp1 confers cisplatin resistance in epithelial ovarian cancer cells.

Authors:  Yanwei Luo; Rong Gui
Journal:  J Gynecol Oncol       Date:  2020-09       Impact factor: 4.401
  1 in total

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