Literature DB >> 31101749

Fatal colchicine intoxication by ingestion of Gloriosa superba tubers.

Karthik Gunasekaran1, Divya Elizabeth Mathew1, Thomas Isaiah Sudarsan2, Ramya Iyyadurai1.   

Abstract

Gloriosa superba is an ornamental herb, wildly found in the tropics especially in the southern parts of India and Sri Lanka. All parts of the plants are toxic, especially the tuberous rhizomes in view of their high content of colchicines and its derivatives. We report a case of fatal ingestion of the tubers of G. superba, with an intention of deliberate self harm, leading to systemic coagulopathy and progressive multiple organ dysfunctions. The patient was managed with intralipid rescue therapy, plasmapheresis, haemodialysis and intensive care. The ease of availability makes plant poisons, a common method of deliberate self-harm in South India. This report reiterates the need for clinician's awareness of common toxidromes associated with plant poisons. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  poisoning; toxicology

Mesh:

Substances:

Year:  2019        PMID: 31101749      PMCID: PMC6536255          DOI: 10.1136/bcr-2018-228718

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  17 in total

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Journal:  Vet Hum Toxicol       Date:  1990-12

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Review 4.  Intravenous lipid emulsion as antidote: a summary of published human experience.

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Journal:  Emerg Med Australas       Date:  2011-04-07       Impact factor: 2.151

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Journal:  Emerg Med J       Date:  2002-05       Impact factor: 2.740

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Authors:  C Putterman; E Ben-Chetrit; Y Caraco; M Levy
Journal:  Semin Arthritis Rheum       Date:  1991-12       Impact factor: 5.532

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Authors:  Smael Labib; Saïd Boujraf; Adnan Berdai; Mustapha Harandou
Journal:  Saudi J Anaesth       Date:  2014-07
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