Literature DB >> 31099349

A novel fluorescent assay for the ultrasensitive detection of miRNA-21 with the use of G-quadruplex structures as an immobilization material for a signal indicator.

Ze-Zhou Yang1, Zhi-Bin Wen, Xin Peng, Ya-Qin Chai, Wen-Bin Liang, Ruo Yuan.   

Abstract

In this work, a novel fluorescent assay was proposed for the ultrasensitive detection of microRNA-21 (miRNA-21) based on the efficient immobilization of protoporphyrin IX (PPIX) as signal indicators in massive G-quadruplex structures obtained by target recycling, three-dimensional DNA walker and a rolling circle amplification (RCA) coupled cascade nucleic acid amplification strategy.

Entities:  

Mesh:

Substances:

Year:  2019        PMID: 31099349     DOI: 10.1039/c9cc01850f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

Review 1.  The Red Color of Life Transformed - Synthetic Advances and Emerging Applications of Protoporphyrin IX in Chemical Biology.

Authors:  Elisabeth Sitte; Mathias O Senge
Journal:  European J Org Chem       Date:  2020-03-30

2.  Accurate Detection of Target MicroRNA in Mixed Species of High Sequence Homology Using Target-Protection Rolling Circle Amplification.

Authors:  Bin Zhang; Shuo Li; Yifu Guan; Ying Yuan
Journal:  ACS Omega       Date:  2021-01-07

3.  Coupling nucleic acid circuitry with the CRISPR-Cas12a system for universal and signal-on detection.

Authors:  Rujian Zhao; Chunxu Yu; Baiyang Lu; Bingling Li
Journal:  RSC Adv       Date:  2022-04-04       Impact factor: 3.361

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.