Literature DB >> 31097984

Treatment of Alzheimer's by PROTAC-Tau Protein Degradation.

Robert B Kargbo1.   

Abstract

Entities:  

Year:  2019        PMID： 31097984      PMCID： PMC6511954          DOI： 10.1021/acsmedchemlett.9b00083

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


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  5 in total

Review 1.  Alpha 7 nicotinic acetylcholine receptor and its effects on Alzheimer's disease.

Authors:  Kai-Ge Ma; Yi-Hua Qian
Journal:  Neuropeptides       Date:  2018-12-18       Impact factor: 3.286

2.  Targeted Degradation of MDM2 as a New Approach to Improve the Efficacy of MDM2-p53 Inhibitors.

Authors:  Ryan P Wurz; Victor J Cee
Journal:  J Med Chem       Date:  2018-12-21       Impact factor: 7.446

Review 3.  Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy.

Authors:  Philipp Ottis; Craig M Crews
Journal:  ACS Chem Biol       Date:  2017-03-20       Impact factor: 5.100

Review 4.  Protac-Induced Protein Degradation in Drug Discovery: Breaking the Rules or Just Making New Ones?

Authors:  Ian Churcher
Journal:  J Med Chem       Date:  2017-12-19       Impact factor: 7.446

Review 5.  The PROTAC technology in drug development.

Authors:  Yutian Zou; Danhui Ma; Yinyin Wang
Journal:  Cell Biochem Funct       Date:  2019-01-02       Impact factor: 3.685
  5 in total
  11 in total

1.  Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality.

Authors:  Philip P Chamberlain; Laura A D'Agostino; J Michael Ellis; Joshua D Hansen; Mary E Matyskiela; Joseph J McDonald; Jennifer R Riggs; Lawrence G Hamann
Journal:  ACS Med Chem Lett       Date:  2019-11-12       Impact factor: 4.345

Review 2.  The Crosstalk Between Pathological Tau Phosphorylation and Mitochondrial Dysfunction as a Key to Understanding and Treating Alzheimer's Disease.

Authors:  Sanjib Guha; Gail V W Johnson; Keith Nehrke
Journal:  Mol Neurobiol       Date:  2020-08-26       Impact factor: 5.590

Review 3.  Phosphorylated tau targeted small-molecule PROTACs for the treatment of Alzheimer's disease and tauopathies.

Authors:  Pradeepkiran Jangampalli Adi; P Hemachandra Reddy
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2021-04-30       Impact factor: 6.633

Review 4.  Targeting tau: Clinical trials and novel therapeutic approaches.

Authors:  Lawren VandeVrede; Adam L Boxer; Manuela Polydoro
Journal:  Neurosci Lett       Date:  2020-05-04       Impact factor: 3.197

5.  De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.

Authors:  Christopher Heim; Dimanthi Pliatsika; Farnoush Mousavizadeh; Kerstin Bär; Birte Hernandez Alvarez; Athanassios Giannis; Marcus D Hartmann
Journal:  J Med Chem       Date:  2019-07-12       Impact factor: 7.446

Review 6.  PROTACs- a game-changing technology.

Authors:  Markella Konstantinidou; Jingyao Li; Bidong Zhang; Zefeng Wang; Shabnam Shaabani; Frans Ter Brake; Khaled Essa; Alexander Dömling
Journal:  Expert Opin Drug Discov       Date:  2019-09-20       Impact factor: 6.098

7.  Light-induced control of protein destruction by opto-PROTAC.

Authors:  Jing Liu; He Chen; Leina Ma; Zhixiang He; Dong Wang; Yi Liu; Qian Lin; Tinghu Zhang; Nathanael Gray; H Ümit Kaniskan; Jian Jin; Wenyi Wei
Journal:  Sci Adv       Date:  2020-02-21       Impact factor: 14.136

Review 8.  Tau Oligomers Neurotoxicity.

Authors:  Grazyna Niewiadomska; Wiktor Niewiadomski; Marta Steczkowska; Anna Gasiorowska
Journal:  Life (Basel)       Date:  2021-01-06

Review 9.  Major Advances in Targeted Protein Degradation: PROTACs, LYTACs, and MADTACs.

Authors:  Shanique Alabi; Craig Crews
Journal:  J Biol Chem       Date:  2021-04-08       Impact factor: 5.157

Review 10.  Acetylcholinesterase: The "Hub" for Neurodegenerative Diseases and Chemical Weapons Convention.

Authors:  Samir F de A Cavalcante; Alessandro B C Simas; Marcos C Barcellos; Victor G M de Oliveira; Roberto B Sousa; Paulo A de M Cabral; Kamil Kuča; Tanos C C França
Journal:  Biomolecules       Date:  2020-03-07
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