Literature DB >> 31096041

Management of Uncomplicated Acute Appendicitis as Day Case Surgery: Can Outcomes of a Prospective Study Be Reproduced in Real Life?

Charles Sabbagh1, Loréna Masseline2, Gérard Grelpois2, Alexandre Ntouba3, Jeanne Dembinski1, Jean-Marc Regimbeau4.   

Abstract

BACKGROUND: The feasibility of day case surgery (DCS) appendectomy for uncomplicated acute appendicitis (UCAA) was evaluated by the prospective AppendAmbu (Feasibility of Outpatient Appendectomy for Acute Appendicitis) study (ClinicalTrials.gov ID NCT01839435). The aim of this study was to evaluate the real-life feasibility of DCS for UCAA. STUDY
DESIGN: This single-center, retrospective, non-interventional study was conducted after the AppendAmbu study and included UCAA only. The primary end point was DCS success rate (ie length of stay <12 hours) in the intention-to-treat population (all patients with UCAA) and in the per-protocol population (population with UCAA and no preoperative and intraoperative exclusion criteria). The secondary end points were to determine the DCS quality criteria to evaluate and compare the morbidity and mortality of DCS and conventional hospitalization for UCAA (Clavien, Comprehensive Complication Index) and to externally validate the St Antoine criteria for the selection of patients for DCS.
RESULTS: From January 2016 to September 2017, two hundred and ninety-six patients underwent operations for acute appendicitis. The proportion of patients with successful DCS management was 27% in the intention-to-treat population and 95% in the per-protocol population. The unplanned consultation rate was 15%, the unplanned hospitalization rate was 4%, and the unplanned reoperation rate was 0%. The postoperative morbidity of patients managed by DCS was not different from that of patients managed in conventional hospitalization. The DCS success rate was 0%, with a St Antoine score of 0, and 80% of patients had a St Antoine score of 5 (p < 0.0001).
CONCLUSIONS: Day case surgery constitutes progress in surgery as a result of enhanced recovery programs. It avoids unnecessary prolonged hospitalization.
Copyright © 2019. Published by Elsevier Inc.

Entities:  

Year:  2019        PMID: 31096041     DOI: 10.1016/j.jamcollsurg.2019.04.031

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  6 in total

1.  Same-day discharge after appendectomy for acute appendicitis: a systematic review and meta-analysis.

Authors:  Elisabeth M L de Wijkerslooth; Jay M Bakas; Joost van Rosmalen; Anne Loes van den Boom; Bas P L Wijnhoven
Journal:  Int J Colorectal Dis       Date:  2021-02-11       Impact factor: 2.571

Review 2.  [Antibiotics alone as an alternative to appendectomy for uncomplicated acute appendicitis in adults: Changes in treatment modalities related to the COVID-19 health crisis].

Authors:  M Collard; Z Lakkis; J Loriau; D Mege; C Sabbagh; J H Lefevre; L Maggiori
Journal:  J Chir Visc       Date:  2020-04-30

Review 3.  Antibiotics alone as an alternative to appendectomy for uncomplicated acute appendicitis in adults: Changes in treatment modalities related to the COVID-19 health crisis.

Authors:  M Collard; Z Lakkis; J Loriau; D Mege; C Sabbagh; J H Lefevre; L Maggiori
Journal:  J Visc Surg       Date:  2020-04-24       Impact factor: 2.043

4.  Appendicitis during the COVID-19 pandemic: lessons learnt from a district general hospital.

Authors:  Heather C M Pringle; Urszula Donigiewicz; Melissa-Rose Bennett; Eleanor Walker; George E Fowler; Sunil Narang; Susan Ball; Robert M Bethune
Journal:  BMC Surg       Date:  2021-05-12       Impact factor: 2.102

5.  The value of post-operative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis: a prospective, randomized, double-blinded, placebo-controlled phase III study (ABAP study).

Authors:  C Sabbagh; N Siembida; H Dupont; M Diouf; J L Schmit; S Boddaert; J M Regimbeau
Journal:  Trials       Date:  2020-06-01       Impact factor: 2.279

6.  Single-port laparoscopic appendectomy using a needle-type grasping forceps for selective adult patients with acute uncomplicated appendicitis.

Authors:  Yang Chen; Yanjie Liu; Shigang Guo; Jieqing Yuan; Xiaojun Li
Journal:  J Surg Case Rep       Date:  2022-01-14
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.