Amperometric sensing of hydrazine by using single gold nanopore electrodes filled with Prussian Blue and coated with polypyrrole and carbon dots.

A nanoprobe for hydrazine sensing is described that is making use of a single gold nanopore electrode (SAuNPEs) that was modified by electro-deposition of Prussian Blue (PB) and then coated with a thin membrane of polypyrrole and carbon dots in order to enhance stability and catalytic activity. Best operated at a low potential of 0.3 V vs. Ag/AgCl, the nanosensor display good electrocatalytic activity towards the oxidation of hydrazine, with a linear response in the 0.5-80 μM hydrazine concentration range and a 0.18 μM detection limit (at S/N = 3). The method was applied to the determination of hydrazine in human urine. Graphical abstract Schematic presentation of the electrocatalytic oxidation of hydrazine using a single gold nanopore electrode that was modified by electro-deposition of Prussian Blue and then coated with a thin membrane of polypyrrole and carbon dots.