| Literature DB >> 31092709 |
Francis Guillemin1,2, Camille Ricatte3,4, Annica Barcenilla-Wong3,4, Amandine Schoumacker3,4, Marita Cross3,4, Camille Alleyrat3,4, Thomas Buttel3,4, Michel Cembalo3,4, Hakima Manseur3,4, Hema Urban3,4, Bruno Fautrel3,4, Philip G Conaghan3,4, Gillian Hawker3,4, Claudia Rutherford3,4, Lyn March3,4, Elisabeth Spitz3,4, David J Hunter3,4.
Abstract
Flare in knee and hip osteoarthritis (OA) is more than just an exacerbation of pain. Unstructured, semistructured, and focus group interviews followed by Delphi surveys with patients and health professionals (HP) generated candidate domains of an OA flare. Content analysis of interviews with 29 patients and 16 HP extracted 180 statements, which were grouped into 9 clusters. Delphi consensus with 50 patients (Australia, Canada, and France) and 116 HP (17 countries on 4 continents) identified 5 flare domains: pain, swelling, stiffness, psychological aspects, and effect of symptoms. Elements for a preliminary definition of an OA flare are proposed. Registered at clinicaltrials.gov NCT02892058.Entities:
Keywords: DOMAIN; FLARE; HIP; KNEE; OMERACT; OSTEOARTHRITIS
Year: 2019 PMID： 31092709 DOI： 10.3899/jrheum.181085
Source DB: PubMed Journal: J Rheumatol ISSN： 0315-162X Impact factor: 4.666