Literature DB >> 31092466

Prognosis of Early-stage Part-solid and Pure-solid Lung Adenocarcinomas.

Fumihiko Kinoshita1, Gouji Toyokawa1, Taichi Matsubara1, Yuka Kozuma1, Naoki Haratake1, Shinkichi Takamori1, Takaki Akamine1, Fumihiko Hirai1, Tomoyoshi Takenaka2, Tetsuzo Tagawa3, Yoshihiko Maehara1.   

Abstract

BACKGROUND/AIM: In the new TNM classification (8th edition) of lung cancer, T category is defined based on the solid component size; therefore, part solid type (PST) with and solid type (ST) without ground glass opacity (GGO) are categorized as same T value according to their solid component sizes. However, differences between these tumors have not been clarified. Patients and Methods The study included 274 pStage I lung adenocarcinoma patients who had undergone surgery at our Institution from 2003 to 2012. Their tumors were classified as pure GGO, PST, and ST. After propensity score matching for solid component size, we compared prognoses between PST and ST.
RESULTS: The same percentage was noted for PST and ST tumors (119/274; 43.4%). After propensity score matching, the disease-free survival (DFS) was significantly worse in ST than PST (5-year DFS: 69.2% versus 88.7%; p=0.0241).
CONCLUSION: Prognoses of PST and ST adenocarcinomas differ even when their solid component sizes are the same. Copyright
© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Lung adenocarcinoma; TNM classification; propensity score matching

Mesh:

Year:  2019        PMID: 31092466     DOI: 10.21873/anticanres.13391

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  5 in total

1.  Iodine-related attenuation in contrast-enhanced dual-energy computed tomography in small-sized solid-type lung cancers is associated with the postoperative prognosis.

Authors:  Shingo Iwano; Shinichiro Kamiya; Rintaro Ito; Shota Nakamura; Shinji Naganawa
Journal:  Cancer Imaging       Date:  2021-01-07       Impact factor: 3.909

2.  Prognostic value of ground glass opacity on computed tomography in pathological stage I pulmonary adenocarcinoma: A meta-analysis.

Authors:  Xue-Lin Pan; Zi-Ling Liao; Hui Yao; Wei-Jie Yan; De-Ying Wen; Yan Wang; Zhen-Lin Li
Journal:  World J Clin Cases       Date:  2021-11-26       Impact factor: 1.337

3.  Relationship between consolidation tumor ratio and tumor-infiltrating lymphocytes in small-sized lung adenocarcinoma.

Authors:  Yuki Ono; Tetsuzo Tagawa; Fumihiko Kinoshita; Naoki Haratake; Kazuki Takada; Mikihiro Kohno; Tomoyoshi Takenaka; Takeshi Kamitani; Mototsugu Shimokawa; Yoshinao Oda; Masaki Mori; Tomoharu Yoshizumi
Journal:  Thorac Cancer       Date:  2022-07-06       Impact factor: 3.223

4.  Comparison of PD-L1 Expression Status between Pure-Solid Versus Part-Solid Lung Adenocarcinomas.

Authors:  Kenichi Suda; Masaki Shimoji; Shigeki Shimizu; Katsuaki Sato; Masato Chiba; Kenji Tomizawa; Toshiki Takemoto; Junichi Soh; Tetsuya Mitsudomi
Journal:  Biomolecules       Date:  2019-09-07

5.  Verification of the eighth edition of the UICC-TNM classification on surgically resected lung adenocarcinoma: Comparison with previous classification in a local center.

Authors:  Hiroshi Minato; Kazuyoshi Katayanagi; Hiroshi Kurumaya; Nobuhiro Tanaka; Hideki Fujimori; Yoshio Tsunezuka; Takeshi Kobayashi
Journal:  Cancer Rep (Hoboken)       Date:  2021-06-24
  5 in total

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