Literature DB >> 31091221

Epidural Analgesia Improves Postoperative Pain Control but Impedes Early Discharge in Patients Undergoing Pancreatic Surgery.

Stephanie S Kim1, Xiaojuan Niu1, Irmina A Elliott1, Jerry P Jiang1, Amanda M Dann1, Lauren M Damato1, Hallie Chung1, Mark D Girgis1, Jonathan C King1, O Joe Hines1, Siamak Rahman2, Timothy R Donahue.   

Abstract

OBJECTIVES: The aim of this study was to evaluate the impact of epidural analgesia (EA) on postoperative length of stay (LOS), expeditious discharge, and pain relief after pancreaticoduodenectomy (PD) and distal pancreatectomy (DP).
METHODS: Retrospective reviews of 2014-2015 American College of Surgeons National Surgical Quality Improvement Program databases and our institutional pancreatic surgery database were conducted.
RESULTS: On univariate analysis, EA was associated with statistically significant longer lengths of stay for both PD and DP. On comparative analysis at mode LOS, discharged before versus after 7 days for PD and 6 days for DP, EA was a significant predictor for the longer groups for both procedures on multivariable analysis (PD, odds ratio of 1.465, P < 0.001; DP, odds ratio of 1.471, P = 0.004). On review of our institution's pancreatic surgery database, patient-reported pain scores were significantly lower in the EA groups than intravenous narcotics groups on the day of surgery only for both PD and DP.
CONCLUSIONS: Epidural analgesia was associated with longer LOS with a most pronounced effect on early discharge after surgery for patients undergoing open PD and DP. It only resulted in superior pain control on the day of surgery.

Entities:  

Mesh:

Year:  2019        PMID: 31091221      PMCID: PMC6521855          DOI: 10.1097/MPA.0000000000001311

Source DB:  PubMed          Journal:  Pancreas        ISSN: 0885-3177            Impact factor:   3.327


  14 in total

1.  Peri-operative epidural may not be the preferred form of analgesia in select patients undergoing pancreaticoduodenectomy.

Authors:  Trevor M Axelrod; Bernardino M Mendez; Gerard J Abood; James M Sinacore; Gerard V Aranha; Margo Shoup
Journal:  J Surg Oncol       Date:  2014-10-31       Impact factor: 3.454

2.  Improved peri-operative outcomes with epidural analgesia in patients undergoing a pancreatectomy: a nationwide analysis.

Authors:  Dominic E Sanford; William G Hawkins; Ryan C Fields
Journal:  HPB (Oxford)       Date:  2015-02-28       Impact factor: 3.647

3.  High performing whipple patients: factors associated with short length of stay after open pancreaticoduodenectomy.

Authors:  Grace C Lee; Zhi Ven Fong; Cristina R Ferrone; Sarah P Thayer; Andrew L Warshaw; Keith D Lillemoe; Carlos Fernández-del Castillo
Journal:  J Gastrointest Surg       Date:  2014-08-05       Impact factor: 3.452

Review 4.  Analgesia after open abdominal surgery in the setting of enhanced recovery surgery: a systematic review and meta-analysis.

Authors:  Michael J Hughes; Nicholas T Ventham; Stephen McNally; Ewen Harrison; Stephen Wigmore
Journal:  JAMA Surg       Date:  2014-12       Impact factor: 14.766

Review 5.  Enhanced recovery pathways in pancreatic surgery: State of the art.

Authors:  Nicolò Pecorelli; Sara Nobile; Stefano Partelli; Luca Cardinali; Stefano Crippa; Gianpaolo Balzano; Luigi Beretta; Massimo Falconi
Journal:  World J Gastroenterol       Date:  2016-07-28       Impact factor: 5.742

6.  Continuous epidural infusion of ropivacaine for postoperative analgesia after major abdominal surgery: comparative study with i.v. PCA morphine.

Authors:  C Jayr; M Beaussier; U Gustafsson; Y Leteurnier; N Nathan; B Plaud; G Tran; C Varlet; J Marty
Journal:  Br J Anaesth       Date:  1998-12       Impact factor: 9.166

7.  Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids: a meta-analysis.

Authors:  Christopher L Wu; Seth R Cohen; Jeffrey M Richman; Andrew J Rowlingson; Genevieve E Courpas; Kristin Cheung; Elaina E Lin; Spencer S Liu
Journal:  Anesthesiology       Date:  2005-11       Impact factor: 7.892

8.  Negligible effect of perioperative epidural analgesia among patients undergoing elective gastric and pancreatic resections.

Authors:  Dhruvil R Shah; Erin Brown; Jack E Russo; Chin-Shang Li; Steve R Martinez; Jodi M Coates; Richard J Bold; Robert J Canter
Journal:  J Gastrointest Surg       Date:  2013-01-24       Impact factor: 3.452

9.  Comparison of the effects of patient-controlled epidural and intravenous analgesia on postoperative bowel function after laparoscopic gastrectomy: a prospective randomized study.

Authors:  Jin Sun Cho; Hyoung-Il Kim; Ki-Young Lee; Taeil Son; Sun Joon Bai; Haegi Choi; Young Chul Yoo
Journal:  Surg Endosc       Date:  2017-04-07       Impact factor: 4.584

10.  Epidural analgesia for pancreatoduodenectomy: a critical appraisal.

Authors:  Wande B Pratt; Richard A Steinbrook; Shishir K Maithel; Tsafrir Vanounou; Mark P Callery; Charles M Vollmer
Journal:  J Gastrointest Surg       Date:  2008-02-09       Impact factor: 3.452

View more
  3 in total

1.  [Efficacy of local infiltration of ropivacaine combined with multimodal analgesia with parecoxib for perioperative analgesia in patients undergoing pancreaticoduodenectomy].

Authors:  Jinhua Feng; Ka Li; Huan Feng; Qiang Han; Min Gao; Ruihua Xu
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2019-07-30

2.  Analgesic effects of ultrasound-guided fourquadrant transversus abdominis plane in patients with cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: a prospective, randomized, controlled study.

Authors:  Jaegyok Song; Nayoung Choi; Minji Kang; Sung Mi Ji; Dong-Wook Kim; Min A Kwon
Journal:  Anesth Pain Med (Seoul)       Date:  2022-01-19

Review 3.  Postoperative Pain Relief after Pancreatic Resection: Systematic Review and Meta-Analysis of Analgesic Modalities.

Authors:  Nasreen Akter; Bathiya Ratnayake; Daniel B Joh; Sara-Jane Chan; Emily Bonner; Sanjay Pandanaboyana
Journal:  World J Surg       Date:  2021-06-29       Impact factor: 3.352

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.