Literature DB >> 31090268

Roles of hyaluronan in cardiovascular and nervous system disorders.

Hong-Yan Ding1, Ya-Nan Xie1, Qiang Dong1, Koji Kimata2, Yoshihiro Nishida3, Naoki Ishiguro3, Li-Sheng Zhuo3.   

Abstract

Hyaluronan is a widely occurring extracellular matrix molecule, which is not only a supporting structural component, but also an active regulator of cellular functions. The chemophysical and biological properties of hyaluronan are greatly affected by its molecular size and several hyaluronan-binding proteins, making hyaluronan a fascinating molecule with great functional diversity. This review summarizes our current understanding of the roles of hyaluronan in cardiovascular and nervous system disorders, such as atherosclerosis, myocardial infarction, and stroke, with the aim to provide a foundation for future research and clinical trials.

Entities:  

Keywords:  Hyaluronic acid; Extracellular matrix; Cardiovascular vessel; Heart; Brain

Mesh：

Substances：

Year:  2019        PMID： 31090268      PMCID： PMC6568231          DOI： 10.1631/jzus.B1900155

Source DB:  PubMed          Journal:  J Zhejiang Univ Sci B        ISSN： 1673-1581            Impact factor:   3.066


  5 in total

1.  Bioinformatic analysis for potential biological processes and key targets of heart failure-related stroke.

Authors:  Chiyu Liu; Sixu Chen; Haifeng Zhang; Yangxin Chen; Qingyuan Gao; Zhiteng Chen; Zhaoyu Liu; Jingfeng Wang
Journal:  J Zhejiang Univ Sci B       Date:  2021 Sept 15       Impact factor: 3.066

Review 2.  Reverse Adverse Immune Microenvironments by Biomaterials Enhance the Repair of Spinal Cord Injury.

Authors:  Hengyi Wang; Yuanliang Xia; Baoqin Li; Yuehong Li; Changfeng Fu
Journal:  Front Bioeng Biotechnol       Date:  2022-05-13

3.  Cornuside alleviates experimental autoimmune encephalomyelitis by inhibiting Th17 cell infiltration into the central nervous system.

Authors:  Rongbo Zhang; Jin Liu; Bin Xu; You Wu; Shunli Liang; Qiang Yuan
Journal:  J Zhejiang Univ Sci B       Date:  2021-05-15       Impact factor: 3.066

Review 4.  The scrambled story between hyaluronan and glioblastoma.

Authors:  Matías Arturo Pibuel; Daniela Poodts; Mariángeles Díaz; Silvia Elvira Hajos; Silvina Laura Lompardía
Journal:  J Biol Chem       Date:  2021-03-17       Impact factor: 5.157

5.  Shock-Induced Damage Mechanism of Perineuronal Nets.

Authors:  Khandakar Abu Hasan Al Mahmud; Fuad Hasan; Md Ishak Khan; Ashfaq Adnan
Journal:  Biomolecules       Date:  2021-12-22
  5 in total

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