Literature DB >> 31086931

Metal-nucleobase hybrid nanoparticles for enhancing the activity and stability of metal-activated enzymes.

Jie He1, Shanshan Sun, Mingzhu Lu, Qipeng Yuan, Yanhui Liu, Hao Liang.   

Abstract

A novel strategy for enhancing the activity and stability of metal-activated enzymes by allosteric control and confinement of metal-nulceobase hybrid coordination was reported in this study. Despite the lack of active Mg2+ ions, methionine adenosyltransferase (MAT) immobilized by Zn2(adenine) still exhibited robust catalytic activity and stability at pH 3 and 80 °C.

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Year:  2019        PMID: 31086931     DOI: 10.1039/c9cc03155c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

Review 1.  Development of biological metal-organic frameworks designed for biomedical applications: from bio-sensing/bio-imaging to disease treatment.

Authors:  Huai-Song Wang; Yi-Hui Wang; Ya Ding
Journal:  Nanoscale Adv       Date:  2020-07-31
  1 in total

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