Literature DB >> 31080669

Comment on "Pulmonary Function Tests in Hypertensive Patients Attending Zewditu Memorial Hospital, Addis Ababa, Ethiopia".

Yusuf Ziya Şener1, Vedat Hekimsoy1, Metin Okşul1.   

Abstract

Entities:  

Year:  2019        PMID: 31080669      PMCID: PMC6475545          DOI: 10.1155/2019/5167018

Source DB:  PubMed          Journal:  Int J Hypertens            Impact factor:   2.420


× No keyword cloud information.
We have read with great interest the article published by Birhan et al., which was about pulmonary function tests in patients with hypertension [1]. It is worth noting that patients using beta blockers were excluded from the study and some parameters of the pulmonary function tests were significantly lower in patients with hypertension than in healthy counterparts. It is well known that antihypertensive medications have certain effects on pulmonary functions. Beta blocking agents cause bronchoconstriction, exacerbating attacks in patients with asthma and COPD. Dry cough is a hallmark complication of treatment with ACE inhibitors. ACE degrades biologically active peptides, including bradykinin, and substance P, and ACE inhibitors lead to accumulation of these peptides. Therefore, ACE inhibitors may cause bronchoconstriction. It is also demonstrated that furosemide has preventive effects on bronchoconstriction. Hydrochlorothiazide can cause interstitial pneumonia in some patients [2]. An association between hypoxia and hypertension is documented, especially in patients with sleep apnea and obesity-hypoventilation syndrome [3]. So restrictive pattern-impaired pulmonary functions may be the cause of increased blood pressure, rather than consequence of hypertension. To conclude, we think that it would be better if the patients' antihypertensive medications and blood oxygen saturation levels were evaluated.
  3 in total

Review 1.  Sympathoexcitation and arterial hypertension associated with obstructive sleep apnea and cyclic intermittent hypoxia.

Authors:  J Woodrow Weiss; Renaud Tamisier; Yuzhen Liu
Journal:  J Appl Physiol (1985)       Date:  2015-08-06

Review 2.  Drug-induced respiratory disorders: incidence, prevention and management.

Authors:  L Ben-Noun
Journal:  Drug Saf       Date:  2000-08       Impact factor: 5.606

3.  Pulmonary Function Tests in Hypertensive Patients Attending Zewditu Memorial Hospital, Addis Ababa, Ethiopia.

Authors:  Mekuriaw Mesfin Birhan; Yekoye Abebe
Journal:  Int J Hypertens       Date:  2018-11-12       Impact factor: 2.420

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.