Literature DB >> 3108023

Photoreceptor degeneration during infection with various strains of the scrapie agent in hamsters.

N C Buyukmihci, F Goehring-Harmon, R F Marsh.   

Abstract

Hamsters were inoculated intracerebrally with the 22C, 79A, and ME7 strains of the scrapie agent to compare the effects on the retina with those caused by strain 263K. The animals developed clinical signs of encephalopathy. Photoreceptor degeneration occurred in all experimental animals. The changes were similar to those seen in animals infected with the 263K strain of scrapie although somewhat more variable and less extensive.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 3108023     DOI: 10.1016/0014-4886(87)90294-9

Source DB:  PubMed          Journal:  Exp Neurol        ISSN: 0014-4886            Impact factor:   5.330


  1 in total

1.  Temporal Resolution of Misfolded Prion Protein Transport, Accumulation, Glial Activation, and Neuronal Death in the Retinas of Mice Inoculated with Scrapie.

Authors:  M Heather West Greenlee; Melissa Lind; Robyn Kokemuller; Najiba Mammadova; Naveen Kondru; Sireesha Manne; Jodi Smith; Anumantha Kanthasamy; Justin Greenlee
Journal:  Am J Pathol       Date:  2016-08-09       Impact factor: 4.307

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.