Literature DB >> 3107982

Molecular analysis of the locus elav in Drosophila melanogaster: a gene whose embryonic expression is neural specific.

A R Campos, D R Rosen, S N Robinow, K White.   

Abstract

The embryonic lethal abnormal visual system (elav) locus in Drosophila melanogaster, a vital gene mapping within the 1B5-1B9 region of the X-chromosome has been cloned and analysed. Previous developmental analyses have shown that in addition to the embryonic requirement there is a post-embryonic requirement for elav function in the cells of the visual system. A DNA segment containing elav+ function was defined through germ line transformation experiments. This region encodes three embryonic poly(A)+ RNAs and two adult transcripts which are preferentially expressed in the head. In situ hybridization experiments clearly demonstrate that the embryonic expression of elav is restricted to the nervous system.

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Year:  1987        PMID： 3107982      PMCID： PMC553413          DOI： 10.1002/j.1460-2075.1987.tb04772.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  42 in total

1.  Two Drosophila melanogaster tropomyosin genes: structural and functional aspects.

Authors:  C C Karlik; E A Fyrberg
Journal:  Mol Cell Biol       Date:  1986-06       Impact factor: 4.272

2.  The Notch locus of Drosophila melanogaster.

Authors:  S Kidd; T J Lockett; M W Young
Journal:  Cell       Date:  1983-09       Impact factor: 41.582

3.  Transposition of cloned P elements into Drosophila germ line chromosomes.

Authors:  A C Spradling; G M Rubin
Journal:  Science       Date:  1982-10-22       Impact factor: 47.728

4.  Lambda replacement vectors carrying polylinker sequences.

Authors:  A M Frischauf; H Lehrach; A Poustka; N Murray
Journal:  J Mol Biol       Date:  1983-11-15       Impact factor: 5.469

5.  Transcription units of adenovirus type 2. Termination of transcription beyond the poly(A) addition site in early regions 2 and 4.

Authors:  J R Nevins; J M Blanchard; J E Darnell
Journal:  J Mol Biol       Date:  1980-12-15       Impact factor: 5.469

6.  The messenger RNA for alcohol dehydrogenase in Drosophila melanogaster differs in its 5' end in different developmental stages.

Authors:  C Benyajati; N Spoerel; H Haymerle; M Ashburner
Journal:  Cell       Date:  1983-05       Impact factor: 41.582

7.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

8.  Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms.

Authors:  P Reddy; W A Zehring; D A Wheeler; V Pirrotta; C Hadfield; J C Hall; M Rosbash
Journal:  Cell       Date:  1984-10       Impact factor: 41.582

9.  Size heterogeneity in the 3' end of dihydrofolate reductase messenger RNAs in mouse cells.

Authors:  D R Setzer; M McGrogan; J H Nunberg; R T Schimke
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

10.  Alternative RNA splicing generates transcripts encoding a thorax-specific isoform of Drosophila melanogaster myosin heavy chain.

Authors:  S I Bernstein; C J Hansen; K D Becker; D R Wassenberg; E S Roche; J J Donady; C P Emerson
Journal:  Mol Cell Biol       Date:  1986-07       Impact factor: 4.272
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  39 in total

Review 1.  Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons.

Authors:  E M DeBoer; M L Kraushar; R P Hart; M-R Rasin
Journal:  Neuroscience       Date:  2013-05-30       Impact factor: 3.590

Review 2.  RNA protein interaction in neurons.

Authors:  Robert B Darnell
Journal:  Annu Rev Neurosci       Date:  2013-05-20       Impact factor: 12.449

3.  Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation.

Authors:  Vikki M Weake; Jamie O Dyer; Christopher Seidel; Andrew Box; Selene K Swanson; Allison Peak; Laurence Florens; Michael P Washburn; Susan M Abmayr; Jerry L Workman
Journal:  Genes Dev       Date:  2011-07-15       Impact factor: 11.361

4.  Target specificity of neuronal RNA-binding protein, Mel-N1: direct binding to the 3' untranslated region of its own mRNA.

Authors:  R Abe; K Yamamoto; H Sakamoto
Journal:  Nucleic Acids Res       Date:  1996-06-01       Impact factor: 16.971

5.  Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC.

Authors:  R Abe; E Sakashita; K Yamamoto; H Sakamoto
Journal:  Nucleic Acids Res       Date:  1996-12-15       Impact factor: 16.971

6.  Differential regulation of synchronous versus asynchronous neurotransmitter release by the C2 domains of synaptotagmin 1.

Authors:  Motojiro Yoshihara; Zhuo Guan; J Troy Littleton
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-02       Impact factor: 11.205

7.  Molecular isolation and analysis of the erect wing locus in Drosophila melanogaster.

Authors:  R J Fleming; S M DeSimone; K White
Journal:  Mol Cell Biol       Date:  1989-02       Impact factor: 4.272

8.  A Drosophila gene encoding a protein resembling the human beta-amyloid protein precursor.

Authors:  D R Rosen; L Martin-Morris; L Q Luo; K White
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

9.  Cabeza, a Drosophila gene encoding a novel RNA binding protein, shares homology with EWS and TLS, two genes involved in human sarcoma formation.

Authors:  D T Stolow; S R Haynes
Journal:  Nucleic Acids Res       Date:  1995-03-11       Impact factor: 16.971

10.  Organizational analysis of elav gene and functional analysis of ELAV protein of Drosophila melanogaster and Drosophila virilis.

Authors:  K M Yao; K White
Journal:  Mol Cell Biol       Date:  1991-06       Impact factor: 4.272
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