Jae-Hong Lee1, Ye-Sol Park2, Yeon-Tae Kim2, Do-Hyung Kim2, Seong-Nyum Jeong2. 1. Department of Periodontology, Daejeon Dental Hospital, Institute of Wonkwang Dental Research, Wonkwang University College of Dentistry, 77 Dunsan-ro, Seo-gu, Daejeon, 35233, South Korea. ljaehong@gmail.com. 2. Department of Periodontology, Daejeon Dental Hospital, Institute of Wonkwang Dental Research, Wonkwang University College of Dentistry, 77 Dunsan-ro, Seo-gu, Daejeon, 35233, South Korea.
Abstract
OBJECTIVE: The aim of this study was to evaluate and compare early postoperative discomfort and wound healing outcomes between patients who underwent periodontal surgery with and without enamel matrix derivative (EMD), using retrospective questionnaires and postoperative clinical examinations. MATERIALS AND METHODS: All enrolled patients filled out the self-report questionnaire after suture removal. The severity and duration of subjective pain and swelling were evaluated using visual analog scale (VAS) scores and wound healing parameters (dehiscence/fenestration, spontaneous bleeding, persistent swelling, and ulceration). Chi-squared tests, two-tailed independent t tests, analysis of variance, and multiple logistic regression analysis were performed to identify significant differences between the two groups (surgery with EMD and surgery without EMD). RESULTS: The severity of pain and swelling did not differ between patients who underwent surgery with and without EMD, but the durations of pain (P < 0.001) and swelling (P = 0.019) were significantly lower in patients who underwent surgery with EMD. Multivariate analysis with adjustment for confounding variables showed that wound healing outcomes including dehiscence/fenestration, spontaneous bleeding, and ulceration did not differ significantly between the two groups, and only persistent swelling showed significant differences (odds ratio 4.03, 95% CI 1.17-13.78; P = 0.026). CONCLUSIONS: No difference was observed in the severity of early postoperative discomfort and wound healing outcomes between patients who underwent surgery with and without EMD, but shorter durations of postoperative pain and swelling were evident in patients who underwent surgery with EMD. CLINICAL RELEVANCE: Adjunctive EMD used in periodontal surgery has clinical advantages for reducing the durations of postoperative pain and swelling.
OBJECTIVE: The aim of this study was to evaluate and compare early postoperative discomfort and wound healing outcomes between patients who underwent periodontal surgery with and without enamel matrix derivative (EMD), using retrospective questionnaires and postoperative clinical examinations. MATERIALS AND METHODS: All enrolled patients filled out the self-report questionnaire after suture removal. The severity and duration of subjective pain and swelling were evaluated using visual analog scale (VAS) scores and wound healing parameters (dehiscence/fenestration, spontaneous bleeding, persistent swelling, and ulceration). Chi-squared tests, two-tailed independent t tests, analysis of variance, and multiple logistic regression analysis were performed to identify significant differences between the two groups (surgery with EMD and surgery without EMD). RESULTS: The severity of pain and swelling did not differ between patients who underwent surgery with and without EMD, but the durations of pain (P < 0.001) and swelling (P = 0.019) were significantly lower in patients who underwent surgery with EMD. Multivariate analysis with adjustment for confounding variables showed that wound healing outcomes including dehiscence/fenestration, spontaneous bleeding, and ulceration did not differ significantly between the two groups, and only persistent swelling showed significant differences (odds ratio 4.03, 95% CI 1.17-13.78; P = 0.026). CONCLUSIONS: No difference was observed in the severity of early postoperative discomfort and wound healing outcomes between patients who underwent surgery with and without EMD, but shorter durations of postoperative pain and swelling were evident in patients who underwent surgery with EMD. CLINICAL RELEVANCE: Adjunctive EMD used in periodontal surgery has clinical advantages for reducing the durations of postoperative pain and swelling.
Authors: George Furtado Guimarães; Vera Cavalcanti de Araújo; James Carlos Nery; Daiane Cristina Peruzzo; Andresa Borges Soares Journal: Int J Periodontics Restorative Dent Date: 2015 Sep-Oct Impact factor: 1.840