Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Emerging Roles of DNA Glycosylases and the Base Excision Repair Pathway.

Literature DB >> 31078398

Emerging Roles of DNA Glycosylases and the Base Excision Repair Pathway.

Elwood A Mullins¹, Alyssa A Rodriguez¹, Noah P Bradley¹, Brandt F Eichman².

Abstract

The base excision repair (BER) pathway historically has been associated with maintaining genome integrity by eliminating nucleobases with small chemical modifications. In the past several years, however, BER was found to play additional roles in genome maintenance and metabolism, including sequence-specific restriction modification and repair of bulky adducts and interstrand crosslinks. Central to this expanded biological utility are specialized DNA glycosylases - enzymes that selectively excise damaged, modified, or mismatched nucleobases. In this review we discuss the newly identified roles of the BER pathway and examine the structural and mechanistic features of the DNA glycosylases that enable these functions.

Entities: Chemical

Keywords: DNA damage; DNA glycosylase; DNA repair; base excision repair; interstrand crosslink; secondary metabolite

Mesh：

Substances：
DNA
DNA Glycosylases

Year: 2019 PMID： 31078398 PMCID： PMC6699911 DOI： 10.1016/j.tibs.2019.04.006

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

98 in total

1. 2001 Fred Griffith review lecture. Immigration control of DNA in bacteria: self versus non-self.

Authors: Noreen E Murray
Journal: Microbiology Date: 2002-01 Impact factor: 2.777

2. A molecular model for DNA cross-linking by the antitumor agent azinomycin B.

Authors: S Alcaro; R S Coleman
Journal: J Med Chem Date: 2000-07-27 Impact factor: 7.446

3. Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA.

Authors: Tapas K Hazra; Tadahide Izumi; Istvan Boldogh; Barry Imhoff; Yoke W Kow; Pawel Jaruga; Miral Dizdaroglu; Sankar Mitra
Journal: Proc Natl Acad Sci U S A Date: 2002-03-19 Impact factor: 11.205

4. Studies on the mechanism of action of azinomycin B: definition of regioselectivity and sequence selectivity of DNA cross-link formation and clarification of the role of the naphthoate.

Authors: Robert S Coleman; Ronelito J Perez; Christopher H Burk; Antonio Navarro
Journal: J Am Chem Soc Date: 2002-11-06 Impact factor: 15.419

5. Turning On uracil-DNA glycosylase using a pyrene nucleotide switch.

Authors: Y L Jiang; K Kwon; J T Stivers
Journal: J Biol Chem Date: 2001-09-10 Impact factor: 5.157

6. Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA.

Authors: Ingrid Morland; Veslemøy Rolseth; Luisa Luna; Torbjørn Rognes; Magnar Bjørås; Erling Seeberg
Journal: Nucleic Acids Res Date: 2002-11-15 Impact factor: 16.971

7. Yatakemycin, a novel antifungal antibiotic produced by Streptomyces sp. TP-A0356.

Authors: Yasuhiro Igarashi; Katsuyuki Futamata; Tsuyoshi Fujita; Akira Sekine; Hisato Senda; Hideo Naoki; Tamotsu Furumai
Journal: J Antibiot (Tokyo) Date: 2003-02 Impact factor: 2.649

8. Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions.

Authors: Tapas K Hazra; Yoke W Kow; Zafar Hatahet; Barry Imhoff; Istvan Boldogh; Sanath K Mokkapati; Sankar Mitra; Tadahide Izumi
Journal: J Biol Chem Date: 2002-07-03 Impact factor: 5.157

9. A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII.

Authors: Viswanath Bandaru; Sirisha Sunkara; Susan S Wallace; Jeffrey P Bond
Journal: DNA Repair (Amst) Date: 2002-07-17

10. Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols.

Authors: Masashi Takao; Shin-ichiro Kanno; Tatsuya Shiromoto; Rei Hasegawa; Hiroshi Ide; Shogo Ikeda; Altaf H Sarker; Shuji Seki; James Z Xing; X Chris Le; Michael Weinfeld; Kumiko Kobayashi; Jun-ichi Miyazaki; Manja Muijtjens; Jan H J Hoeijmakers; Gijsbertus van der Horst; Akira Yasui; Altraf H Sarker
Journal: EMBO J Date: 2002-07-01 Impact factor: 11.598

24 in total

Review 1. Structural biology of DNA abasic site protection by SRAP proteins.

Authors: Katherine M Amidon; Brandt F Eichman
Journal: DNA Repair (Amst) Date: 2020-06-29

2. An autoinhibitory role for the GRF zinc finger domain of DNA glycosylase NEIL3.

Authors: Alyssa A Rodriguez; Jessica L Wojtaszek; Briana H Greer; Tuhin Haldar; Kent S Gates; R Scott Williams; Brandt F Eichman
Journal: J Biol Chem Date: 2020-09-02 Impact factor: 5.157

3. Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1.

Authors: Irina G Minko; Vladimir L Vartanian; Naoto N Tozaki; Erdem Coskun; Sanem Hosbas Coskun; Pawel Jaruga; Jongchan Yeo; Sheila S David; Michael P Stone; Martin Egli; Miral Dizdaroglu; Amanda K McCullough; R Stephen Lloyd
Journal: DNA Repair (Amst) Date: 2019-11-02

4. The structure of the Thermococcus gammatolerans McrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs.

Authors: Christopher J Hosford; Anthony Q Bui; Joshua S Chappie
Journal: J Biol Chem Date: 2019-12-10 Impact factor: 5.157

5. DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B₁-Induced Formamidopyrimidine Guanine Adduct.

Authors: Rachana Tomar; Irina G Minko; Andrew H Kellum; Markus W Voehler; Michael P Stone; Amanda K McCullough; R Stephen Lloyd
Journal: Chem Res Toxicol Date: 2021-02-17 Impact factor: 3.739