Literature DB >> 3107778

Osteonectin content in human osteogenesis imperfecta bone shows a range similar to that of two bovine models of OI.

L W Fisher, M A Drum, P G Robey, K M Conn, J D Termine.   

Abstract

Samples of human osteogenesis imperfecta (OI) bone were analyzed for osteonectin content by SDS gel electrophoresis and immunodetection on Western blots. The OI bone osteonectin content varied from normal to severely depressed. Previously, we showed that two clinically identical but genetically unrelated bovine models of OI were differentiated biochemically by their bone osteonectin content: one OI model had normal bone osteonectin while the other was severely depressed in this parameter. The data in this pilot study suggest that further investigation of bone osteonectin content may prove useful in the clinical assessment of human OI cases.

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Year:  1987        PMID： 3107778     DOI： 10.1007/bf02555258

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  27 in total

1.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

2.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

3.  Synthesis of a shortened pro-alpha 2(I) chain and decreased synthesis of pro-alpha 2(I) chains in a proband with osteogenesis imperfecta.

Authors:  W J de Wet; T Pihlajaniemi; J Myers; T E Kelly; D J Prockop
Journal:  J Biol Chem       Date:  1983-06-25       Impact factor: 5.157

4.  Osteonectin, a bone-specific protein linking mineral to collagen.

Authors:  J D Termine; H K Kleinman; S W Whitson; K M Conn; M L McGarvey; G R Martin
Journal:  Cell       Date:  1981-10       Impact factor: 41.582

5.  Isolation and characterization of native adult osteonectin.

Authors:  R W Romberg; P G Werness; P Lollar; B L Riggs; K G Mann
Journal:  J Biol Chem       Date:  1985-03-10       Impact factor: 5.157

6.  Genetic heterogeneity in osteogenesis imperfecta.

Authors:  D O Sillence; A Senn; D M Danks
Journal:  J Med Genet       Date:  1979-04       Impact factor: 6.318

7.  Lethal osteogenesis imperfecta congenita and a 300 base pair gene deletion for an alpha 1(I)-like collagen.

Authors:  F M Pope; K S Cheah; A C Nicholls; A B Price; F G Grosveld
Journal:  Br Med J (Clin Res Ed)       Date:  1984-02-11

8.  Mineral and collagen-binding proteins of fetal calf bone.

Authors:  J D Termine; A B Belcourt; K M Conn; H K Kleinman
Journal:  J Biol Chem       Date:  1981-10-25       Impact factor: 5.157

9.  Osteogenesis imperfecta: an expanding panorama of variants.

Authors:  D Sillence
Journal:  Clin Orthop Relat Res       Date:  1981-09       Impact factor: 4.176

10.  The molecular defect in an autosomal dominant form of osteogenesis imperfecta. Synthesis of type I procollagen containing cysteine in the triple-helical domain of pro-alpha 1(I) chains.

Authors:  W N de Vries; W J de Wet
Journal:  J Biol Chem       Date:  1986-07-05       Impact factor: 5.157
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  5 in total

1.  Monoclonal antibodies against osteonectin show conservation of epitopes across species.

Authors:  M E Bolander; P G Robey; L W Fisher; K M Conn; B S Prabhakar; J D Termine
Journal:  Calcif Tissue Int       Date:  1989-08       Impact factor: 4.333

2.  Osteopenia and decreased bone formation in osteonectin-deficient mice.

Authors:  A M Delany; M Amling; M Priemel; C Howe; R Baron; E Canalis
Journal:  J Clin Invest       Date:  2000-04       Impact factor: 14.808

3.  Recessive osteogenesis imperfecta caused by missense mutations in SPARC.

Authors:  Roberto Mendoza-Londono; Somayyeh Fahiminiya; Jacek Majewski; Martine Tétreault; Javad Nadaf; Peter Kannu; Etienne Sochett; Andrew Howard; Jennifer Stimec; Lucie Dupuis; Paul Roschger; Klaus Klaushofer; Telma Palomo; Jean Ouellet; Hadil Al-Jallad; John S Mort; Pierre Moffatt; Sergei Boudko; Hans-Peter Bächinger; Frank Rauch
Journal:  Am J Hum Genet       Date:  2015-05-28       Impact factor: 11.025

Review 4.  The effect of the microscopic and nanoscale structure on bone fragility.

Authors:  M E Ruppel; L M Miller; D B Burr
Journal:  Osteoporos Int       Date:  2008-03-04       Impact factor: 4.507

5.  Osteonectin/SPARC polymorphisms in Caucasian men with idiopathic osteoporosis.

Authors:  A M Delany; D J McMahon; J S Powell; D A Greenberg; E S Kurland
Journal:  Osteoporos Int       Date:  2007-12-15       Impact factor: 4.507
  5 in total

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