Literature DB >> 31077174

Correction to: A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer.

Michelle E Penney1, Patrick S Parfrey2, Sevtap Savas1,3, Yildiz E Yilmaz4,5,6.   

Abstract

.

Entities:  

Year:  2019        PMID: 31077174      PMCID: PMC6511186          DOI: 10.1186/s12885-019-5672-7

Source DB:  PubMed          Journal:  BMC Cancer        ISSN: 1471-2407            Impact factor:   4.430


× No keyword cloud information.
Correction to: Penney et al. BMC Cancer (2019) 19:133 https://doi.org/10.1186/s12885-019-5346-5 Following publication of the original article [1], the authors reported that Fig. 3 was mistakenly replaced by Fig. 4. The correct Fig. 3 is given below:
Fig. 3

Kaplan-Meier survival function for the most significant SNPs in the multivariable analysis under the (a) mixture cure model and (b) Cox proportional hazards regression model. n: number of patients in that genotype category; d: number of metastasis in that genotype category. a rs5749032 was the only SNP maintaining genome-wide significance after the multivariable analysis using the mixture cure model. In the rs5749032 GG genotype subgroup, the clear plateau at approximately 80% metastasis-free survival probability indicates the existence of a large proportion of long-term metastasis-free survivors. b In the rs2327990 TT genotype subgroup, all the patients experienced metastasis within approximately the first two years. Therefore, a standard survival analysis method is appropriate

Kaplan-Meier survival function for the most significant SNPs in the multivariable analysis under the (a) mixture cure model and (b) Cox proportional hazards regression model. n: number of patients in that genotype category; d: number of metastasis in that genotype category. a rs5749032 was the only SNP maintaining genome-wide significance after the multivariable analysis using the mixture cure model. In the rs5749032 GG genotype subgroup, the clear plateau at approximately 80% metastasis-free survival probability indicates the existence of a large proportion of long-term metastasis-free survivors. b In the rs2327990 TT genotype subgroup, all the patients experienced metastasis within approximately the first two years. Therefore, a standard survival analysis method is appropriate
  1 in total

1.  A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer.

Authors:  Michelle E Penney; Patrick S Parfrey; Sevtap Savas; Yildiz E Yilmaz
Journal:  BMC Cancer       Date:  2019-02-09       Impact factor: 4.430

  1 in total
  1 in total

1.  A comprehensive analysis of SNPs and CNVs identifies novel markers associated with disease outcomes in colorectal cancer.

Authors:  Yajun Yu; Salem Werdyani; Megan Carey; Patrick Parfrey; Yildiz E Yilmaz; Sevtap Savas
Journal:  Mol Oncol       Date:  2021-08-05       Impact factor: 6.603

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.