Xiao-Guang Ni1, Gui-Qi Wang1, Feng-Ying Hu2, Xin-Mao Xu3, Ling Xu4, Xiao-Qin Liu5, Xue-Song Chen6, Lin Liu7, Xue-Lian Ren8, Yong Yang9, Li Guo10, Ya-Jun Gu11, Jin Hou12, Jun-Wei Zhang13, Yan Yang14, Biao Xing15, Jia Ren16, Hong-Qiang Guo17. 1. Department of Endoscopy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. 2. Department of Otolaryngology Head and Neck Surgery, Inner Mongolia North Hospital, Baotou, China. 3. Department of Otorhinolaryngology, Tengzhou Central People's Hospital, Tengzhou, China. 4. Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Inner, Mongolia Medical University, Hohhot, China. 5. Department of Otorhinolaryngology, Inner Mongolia People's Hospital, Hohhot, China. 6. Department of Otorhinolaryngology, Binzhou City Center Hospital, Binzhou, China. 7. Department of Otolaryngology Head and Neck Surgery, Dalian Municipal Friendship Hospital, Dalian, China. 8. Department of eye and Otorhinolaryngology, Weifang Maternal and Child Care Hospital, Weifang, China. 9. Department of Otolaryngology Head and Neck Surgery, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China. 10. Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China. 11. Department of Otolaryngology Head and Neck Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing, China. 12. Department of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. 13. Department of Otorhinolaryngology, Traditional Chinese Medicine Hospital of Ruzhou City, Ruzhou, China. 14. Department of Otorhinolaryngology, the First People's Hospital of Yunnan Province, Kunming, China. 15. Department of Otorhinolaryngology, Cangzhou Central Hospital, Cangzhou, China. 16. Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China. 17. Department of Otorhinolaryngology, Zaozhuang Municipal Hospital, Zaozhuang, China.
Abstract
OBJECTIVE: To analyse the application of a new narrow-band imaging (NBI) classification in the diagnosis of vocal cord leukoplakia by laryngologists with different levels of laryngoscopic experience and to explore the impact of NBI training programmes on laryngologists' identification of benign and malignant leukoplakia. DESIGN: Prospective multicentre study. SETTING: Tertiary hospitals. PARTICIPANTS: Sixteen laryngologists were divided into less-experienced and experienced groups and received NBI training course. Thirty cases of vocal cord leukoplakia were investigated. MAIN OUTCOME MEASURES: Diagnostic accuracy and interobserver agreement under white light imaging (WLI), before and after NBI training, were analysed among doctors with varying levels of experience. RESULTS: The accuracy in the less-experienced group was significantly lower than that of experience group (0.59 vs 0.69) under WLI. There was no significant difference in the diagnostic accuracy between the less-experienced group and the experienced group before NBI training (0.75 vs 0.74) and after NBI training (0.79 vs 0.83). NBI training could improve the interobserver agreement from fair or moderate to good agreement. CONCLUSION: The new NBI diagnostic classification is helpful for identifying benign and malignant vocal cord leukoplakia. In addition, the NBI training programme can improve the diagnostic accuracy and interobserver agreement of less-experienced doctors to the level of experienced laryngologists.
OBJECTIVE: To analyse the application of a new narrow-band imaging (NBI) classification in the diagnosis of vocal cord leukoplakia by laryngologists with different levels of laryngoscopic experience and to explore the impact of NBI training programmes on laryngologists' identification of benign and malignant leukoplakia. DESIGN: Prospective multicentre study. SETTING: Tertiary hospitals. PARTICIPANTS: Sixteen laryngologists were divided into less-experienced and experienced groups and received NBI training course. Thirty cases of vocal cord leukoplakia were investigated. MAIN OUTCOME MEASURES: Diagnostic accuracy and interobserver agreement under white light imaging (WLI), before and after NBI training, were analysed among doctors with varying levels of experience. RESULTS: The accuracy in the less-experienced group was significantly lower than that of experience group (0.59 vs 0.69) under WLI. There was no significant difference in the diagnostic accuracy between the less-experienced group and the experienced group before NBI training (0.75 vs 0.74) and after NBI training (0.79 vs 0.83). NBI training could improve the interobserver agreement from fair or moderate to good agreement. CONCLUSION: The new NBI diagnostic classification is helpful for identifying benign and malignant vocal cord leukoplakia. In addition, the NBI training programme can improve the diagnostic accuracy and interobserver agreement of less-experienced doctors to the level of experienced laryngologists.
Authors: Alberto Paderno; Cesare Piazza; Francesca Del Bon; Davide Lancini; Stefano Tanagli; Alberto Deganello; Giorgio Peretti; Elena De Momi; Ilaria Patrini; Michela Ruperti; Leonardo S Mattos; Sara Moccia Journal: Front Oncol Date: 2021-03-24 Impact factor: 6.244