Ashley Hinther1, Omar Abdel-Rahman2, Winson Y Cheung2, May Lynn Quan3, Joseph C Dort4,5. 1. Section of Otolaryngology - Head and Neck Surgery, Department of Surgery, Cumming School of Medicine, University of Calgary, HRIC 2A02, 3280 Hospital Dr NW, Calgary, AB, T2N 4Z6, Canada. 2. Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. 3. Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. 4. Section of Otolaryngology - Head and Neck Surgery, Department of Surgery, Cumming School of Medicine, University of Calgary, HRIC 2A02, 3280 Hospital Dr NW, Calgary, AB, T2N 4Z6, Canada. jdort@ucalgary.ca. 5. Ohlson Research Initiative, Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. jdort@ucalgary.ca.
Abstract
BACKGROUND: There are a number of studies in the literature that describe the prevalence, causes, and factors associated with chronic postoperative opioid use, but there is a lack of synthesis of the literature to guide clinicians in optimally managing postoperative pain while avoiding opioid dependence. Thus, the goal of this study was to perform a systematic review of the literature to investigate the prevalence of chronic postoperative opioid use and the associated risk factors. MATERIALS AND METHODS: A systematic search was performed using Ovid Medline and Embase according to PRISMA guidelines. Data were collected on the following outcomes of interest: prevalence of opioid use at 3, 6, and 12 months postoperatively, and risk factors associated with chronic postoperative opioid use. RESULTS: Forty-three articles were included in the final analysis. The mean prevalence of chronic postoperative opioid use in all populations at 3, 6, and 12 months postoperatively was 30.5%, 25.6%, and 25.2%, respectively. The prevalence of patients who developed chronic opioid use at 3, 6, and 12 months postoperatively was 10.4%, 8.5%, and 9.8%, respectively. Forty of the articles analyzed risk factors associated with chronic postoperative opioid use. The most common associated risk factor identified was preoperative opioid use with 27 articles demonstrating a significant association with chronic postoperative opioid use. DISCUSSION: The current opioid crisis is in part secondary to the prevalence of chronic opioid use following surgery. This study identified associated risk factors with chronic postoperative opioid use, which may help identify patients at risk for developing chronic postoperative opioid use.
BACKGROUND: There are a number of studies in the literature that describe the prevalence, causes, and factors associated with chronic postoperative opioid use, but there is a lack of synthesis of the literature to guide clinicians in optimally managing postoperative pain while avoiding opioid dependence. Thus, the goal of this study was to perform a systematic review of the literature to investigate the prevalence of chronic postoperative opioid use and the associated risk factors. MATERIALS AND METHODS: A systematic search was performed using Ovid Medline and Embase according to PRISMA guidelines. Data were collected on the following outcomes of interest: prevalence of opioid use at 3, 6, and 12 months postoperatively, and risk factors associated with chronic postoperative opioid use. RESULTS: Forty-three articles were included in the final analysis. The mean prevalence of chronic postoperative opioid use in all populations at 3, 6, and 12 months postoperatively was 30.5%, 25.6%, and 25.2%, respectively. The prevalence of patients who developed chronic opioid use at 3, 6, and 12 months postoperatively was 10.4%, 8.5%, and 9.8%, respectively. Forty of the articles analyzed risk factors associated with chronic postoperative opioid use. The most common associated risk factor identified was preoperative opioid use with 27 articles demonstrating a significant association with chronic postoperative opioid use. DISCUSSION: The current opioid crisis is in part secondary to the prevalence of chronic opioid use following surgery. This study identified associated risk factors with chronic postoperative opioid use, which may help identify patients at risk for developing chronic postoperative opioid use.
Authors: Ian Carroll; Peter Barelka; Charlie Kiat Meng Wang; Bing Mei Wang; Matthew John Gillespie; Rebecca McCue; Jarred W Younger; Jodie Trafton; Keith Humphreys; Stuart B Goodman; Fredrick Dirbas; Richard I Whyte; Jessica S Donington; Walter B Cannon; Sean Charles Mackey Journal: Anesth Analg Date: 2012-06-22 Impact factor: 5.108
Authors: Chad M Brummett; Jennifer F Waljee; Jenna Goesling; Stephanie Moser; Paul Lin; Michael J Englesbe; Amy S B Bohnert; Sachin Kheterpal; Brahmajee K Nallamothu Journal: JAMA Surg Date: 2017-06-21 Impact factor: 14.766
Authors: Joshua T Anderson; Arnold R Haas; Rick Percy; Stephen T Woods; Uri M Ahn; Nicholas U Ahn Journal: Spine (Phila Pa 1976) Date: 2015-11 Impact factor: 3.468
Authors: Cary S Politzer; Beau J Kildow; Daniel E Goltz; Cynthia L Green; Michael P Bolognesi; Thorsten M Seyler Journal: J Arthroplasty Date: 2017-11-14 Impact factor: 4.757
Authors: Sheyan J Armaghani; Dennis S Lee; Jesse E Bible; Kristin R Archer; David N Shau; Harrison Kay; Chi Zhang; Matthew J McGirt; Clinton J Devin Journal: Spine (Phila Pa 1976) Date: 2014-12-01 Impact factor: 3.468
Authors: Luke B Hartford; Julie Ann M Van Koughnett; Patrick B Murphy; Kelly N Vogt; Richard J Hilsden; Collin Fm Clarke; Laura J Allen; Samuel D Gray; Neil G Parry; Daryl K Gray; Ken A Leslie Journal: J Am Coll Surg Date: 2018-10-22 Impact factor: 6.113
Authors: Max Catchpool; Josh Knight; Jesse T Young; Philip Clarke; Michael J Barrington; Peter F M Choong; Michelle M Dowsey Journal: ANZ J Surg Date: 2019-10-21 Impact factor: 1.872
Authors: Jennifer M Hah; Jodie A Trafton; Balasubramanian Narasimhan; Partha Krishnamurthy; Heather Hilmoe; Yasamin Sharifzadeh; James I Huddleston; Derek Amanatullah; William J Maloney; Stuart Goodman; Ian Carroll; Sean C Mackey Journal: EClinicalMedicine Date: 2020-10-16