Literature DB >> 31073500

Severe Troponin I Elevation and Myocardial Dysfunction in a Child with Scorpion Sting.

Nagehan Aslan1, Dincer Yildizdas1, Ozden Ozgur Horoz1, Didar Arslan1, Celal Varan2, Sevcan Erdem2, Hayri Levent Yılmaz3.   

Abstract

Background  Scorpion sting is a common medical problem and major cause of mortality and morbidity in many countries. The symptoms of envenomation are more severe in the pediatric population. The clinical manifestations of scorpion envenomation appear by activation of sympathetic and parasympathetic nervous system. Envenomation can cause multiorgan dysfunction and death. Case Presentation and Findings  In this case report, we present a pediatric patient from Adana, Southeast Anatolia, with severe scorpion envenomation with Leiurus abdullahbayrami which is an especially dangerous species for children. Severe systolic dysfunction was detected by echocardiography. Troponin I levels elevated significantly and rapidly responded to three doses of antivenom therapy. Conclusion  Early echocardiographic examination is an important procedure for patients with scorpion envenomation. Troponin I is a significant parameter to monitor the degree of cardiac injury. Antivenom therapy is the only recommended specific therapy for children with severe scorpion envenomation due to Leiurus abdullahbayrami . Abnormal echocardiography findings may require repeated doses of scorpion antivenom.

Entities:  

Keywords:  child; high troponin; scorpion; severe systolic dysfunction; three doses of antivenom

Year:  2018        PMID: 31073500      PMCID: PMC6506674          DOI: 10.1055/s-0038-1673624

Source DB:  PubMed          Journal:  J Pediatr Intensive Care        ISSN: 2146-4626


  25 in total

Review 1.  Scorpion sting.

Authors:  S Mahadevan
Journal:  Indian Pediatr       Date:  2000-05       Impact factor: 1.411

2.  On the management of scorpion stings.

Authors:  S B Deshpande; A B Alex
Journal:  Heart       Date:  2000-05       Impact factor: 5.994

3.  Electrocardiographic studies with scorpion (Buthus minax, L. Koch) venom.

Authors:  M Ismail; O H Osman; D Petkovic
Journal:  Toxicon       Date:  1976       Impact factor: 3.033

Review 4.  The cardiovascular system after scorpion envenomation. A review.

Authors:  M Gueron; R Ilia; S Sofer
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5.  Evidence for a direct action of Tityus serrulatus scorpion venom on the cardiac muscle.

Authors:  A L Teixeira; B F Fontoura; L Freire-Maia; C R Machado; E R Camargos; M M Teixeira
Journal:  Toxicon       Date:  2001-05       Impact factor: 3.033

Review 6.  Autonomic effects of some scorpion venoms and toxins.

Authors:  Matthew C E Gwee; Selvanayagam Nirthanan; Hoon-Eng Khoo; Ponnampalam Gopalakrishnakone; R Manjunatha Kini; Li-Sam Cheah
Journal:  Clin Exp Pharmacol Physiol       Date:  2002-09       Impact factor: 2.557

7.  Cardiac troponin I release after severe scorpion envenoming by Tityus serrulatus.

Authors:  Palmira Cupo; Sylvia Evelyn Hering
Journal:  Toxicon       Date:  2002-06       Impact factor: 3.033

8.  Epidemiological and clinical characteristics of scorpionism in children in Sanliurfa, Turkey.

Authors:  Suhendan Adiguzel; Ozcan Ozkan; Bora Inceoglu
Journal:  Toxicon       Date:  2007-01-10       Impact factor: 3.033

9.  Antivenom for critically ill children with neurotoxicity from scorpion stings.

Authors:  Leslie V Boyer; Andreas A Theodorou; Robert A Berg; Joanne Mallie; Ariana Chávez-Méndez; Walter García-Ubbelohde; Stephen Hardiman; Alejandro Alagón
Journal:  N Engl J Med       Date:  2009-05-14       Impact factor: 91.245

10.  Significance of assessment of serum cardiac troponin I and interleukin-8 in scorpion envenomed children.

Authors:  Abdel-Raheem A M Meki; Zeinab M M Mohamed; Hasan M Mohey El-deen
Journal:  Toxicon       Date:  2003-02       Impact factor: 3.033

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