Literature DB >> 31071420

Investigation of the parameters used in fused deposition modeling of poly(lactic acid) to optimize 3D printing sessions.

E Carlier1, S Marquette2, C Peerboom2, L Denis2, S Benali3, J-M Raquez3, K Amighi4, J Goole4.   

Abstract

This study assesses the feasibility of printing implantable devices using 3D printing Fused deposition modeling (FDM) technology. The influence of the deposition temperature, the deposition rate and the layer thickness on the printing process and the physical properties of the devices were evaluated. The filaments were composed of neat poly(lactic acid) (PLA) and blends of different plasticizers (polyethylene glycol 400 (PEG 400), triacetine (TA), acetyltriethyl citrate (ATEC) and triethyl citrate (TEC)) at 10% (w/w). The assessment of thermomechanical characteristics and morphology of both filaments and devices (cylinders and dog bones) were performed. The influence of each parameter was evaluated using a design of experiment (DoE) and the significance of the results was discussed. A large amount of data about the evaluation of FDM process parameters are already available in the literature. However, specific insights needed to be increased into the impact of the use of PLA and plasticized PLA raw material on the feasibility of printing devices in three dimensions. To conclude, the ductility was improved with a high layer thickness, low temperature and using ATEC. Whereas, adhesion was promoted with an increase in temperature, a lower layer thickness and adding TA.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  3D printing; Fused deposition modeling; Poly(lactic acid); Printing parameters; Thermomechanical properties

Mesh:

Substances:

Year:  2019        PMID: 31071420     DOI: 10.1016/j.ijpharm.2019.05.008

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  6 in total

1.  3D printing of bioinspired compartmentalized capsular structure for controlled drug release.

Authors:  Jingwen Li; Mingxin Wu; Wenhui Chen; Haiyang Liu; Di Tan; Shengnan Shen; Yifeng Lei; Longjian Xue
Journal:  J Zhejiang Univ Sci B       Date:  2021-12-15       Impact factor: 3.066

2.  POM/EVA Blends with Future Utility in Fused Deposition Modeling.

Authors:  Mateusz Galeja; Klaudiusz Wypiór; Jan Wachowicz; Przemysław Kędzierski; Aleksander Hejna; Mariusz Marć; Krzysztof Klewicz; Jadwiga Gabor; Hubert Okła; Andrzej Szymon Swinarew
Journal:  Materials (Basel)       Date:  2020-06-29       Impact factor: 3.623

Review 3.  Challenges on optimization of 3D-printed bone scaffolds.

Authors:  Marjan Bahraminasab
Journal:  Biomed Eng Online       Date:  2020-09-03       Impact factor: 2.819

Review 4.  Main Applications and Recent Research Progresses of Additive Manufacturing in Dentistry.

Authors:  Gan Huang; Libo Wu; Jie Hu; Xiongming Zhou; Fei He; Li Wan; Shu-Ting Pan
Journal:  Biomed Res Int       Date:  2022-02-24       Impact factor: 3.411

Review 5.  Hybprinting for musculoskeletal tissue engineering.

Authors:  Jiannan Li; Carolyn Kim; Chi-Chun Pan; Aaron Babian; Elaine Lui; Jeffrey L Young; Seyedsina Moeinzadeh; Sungwoo Kim; Yunzhi Peter Yang
Journal:  iScience       Date:  2022-04-08

6.  Customized Novel Design of 3D Printed Pregabalin Tablets for Intra-Gastric Floating and Controlled Release Using Fused Deposition Modeling.

Authors:  Shrawani Lamichhane; Jun-Bom Park; Dong Hwan Sohn; Sangkil Lee
Journal:  Pharmaceutics       Date:  2019-10-30       Impact factor: 6.321

  6 in total

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