Literature DB >> 31070862

Nummular dermatitis on guselkumab for palmoplantar psoriasis.

Allison Truong1, Stephanie Le2, Maija Kiuru2, Emanual Maverakis2.   

Abstract

A 40-year-old man with chronic history of refractory palmoplantar psoriasis presented with new onset of well-demarcated oval erythematous asteatotic plaques on bilateral shins after starting guselkumab therapy. Histopathology revealed chronic spongiotic dermatitis consistent with a diagnosis of nummular dermatitis. This case highlights a previously unreported adverse event to guselkumab therapy.
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  IL23; Th17; dermatitis; guselkumab; nummular; palmoplantar; psoriasis

Mesh：

Substances：

Year:  2019        PMID： 31070862      PMCID： PMC6688931          DOI： 10.1111/dth.12954

Source DB:  PubMed          Journal:  Dermatol Ther        ISSN： 1396-0296            Impact factor:   2.851


  5 in total

1.  Patients with palmoplantar pustulosis have increased IL-17 and IL-22 levels both in the lesion and serum.

Authors:  Masamoto Murakami; Eva Hagforsen; Vera Morhenn; Akemi Ishida-Yamamoto; Hajime Iizuka
Journal:  Exp Dermatol       Date:  2011-07-07       Impact factor: 3.960

2.  Nummular eczema during isotretinoin treatment.

Authors:  V Bettoli; A Tosti; C Varotti
Journal:  J Am Acad Dermatol       Date:  1987-03       Impact factor: 11.527

3.  Increased peripheral Th17 in patients with pustulosis palmaris et plantaris.

Authors:  Kan Torii; Takuya Furuhashi; Chiyo Saito; Hiroshi Kato; Akiko Nishioka; Emi Nishida; Yoichi Shintani; Akimichi Morita
Journal:  Arch Dermatol Res       Date:  2011-01-13       Impact factor: 3.017

4.  Severe, generalized nummular eczema secondary to interferon alfa-2b plus ribavirin combination therapy in a patient with chronic hepatitis C virus infection.

Authors:  Megan M Moore; David J Elpern; Daniel J Carter
Journal:  Arch Dermatol       Date:  2004-02

5.  Efficacy and Safety of Guselkumab, an Anti-interleukin 23 Monoclonal Antibody, for Palmoplantar Pustulosis: A Randomized Clinical Trial.

Authors:  Tadashi Terui; Satomi Kobayashi; Yukari Okubo; Masamoto Murakami; Keiichiro Hirose; Hiroshi Kubo
Journal:  JAMA Dermatol       Date:  2018-03-01       Impact factor: 10.282
  5 in total
  2 in total

1.  Eczematous eruption after guselkumab treatment for psoriasis.

Authors:  Birgit Reyn; Tom Hillary; Ann Gils
Journal:  JAAD Case Rep       Date:  2019-10-24

Review 2.  Pathogenesis of Paradoxical Reactions Associated with Targeted Biologic Agents for Inflammatory Skin Diseases.

Authors:  Fumi Miyagawa
Journal:  Biomedicines       Date:  2022-06-23
  2 in total

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