Nikolaos Dimasis1, Periklis Koukourikis1, Athanasios Klampatsas1, Persefoni Xirou2, Petros Sountoulides3. 1. Department of Urology - Oncology. "Theagenio" Anticancer Hospital of Thessaloniki. Thessaloniki. Greece. 2. Pathology Laboratory. "Theagenio" Anticancer Hospital of Thessaloniki. Thessaloniki. Greece. 3. Department of Urology - Oncology. "Theagenio" Anticancer Hospital of Thessaloniki. Thessaloniki. Greece. Urology Department. The Pennine Acute Hospitals. NHS Trust. Manchester. U.K.
Abstract
OBJECTIVE: Persistent Müllerian Duct Syndrome (PMDS), one of the causes of male pseudohermaphroditism, is a rare syndrome characterized by the presence of internal female genitalia (uterus, fallopian, tubes, cervix and upper vagina) in otherwise phenotypically and normally virilized men. METHODS: We present the 4th documented case of uterine malignancy in a 45-year-old man with PMDS presenting with lower abdominal protuberance and hematuria. RESULTS: Although testicular malignancies are common in undescended testis associated with PMDS, very few cases of müllerian duct malignancies have been reported. CONCLUSIONS: Persistent mullerian duct syndrome can be associated with aggressive non-testicular malignancies, especially uterine cancer, in normally virilized males.
OBJECTIVE: Persistent Müllerian Duct Syndrome (PMDS), one of the causes of male pseudohermaphroditism, is a rare syndrome characterized by the presence of internal female genitalia (uterus, fallopian, tubes, cervix and upper vagina) in otherwise phenotypically and normally virilized men. METHODS: We present the 4th documented case of uterine malignancy in a 45-year-old man with PMDS presenting with lower abdominal protuberance and hematuria. RESULTS: Although testicular malignancies are common in undescended testis associated with PMDS, very few cases of müllerian duct malignancies have been reported. CONCLUSIONS: Persistent mullerian duct syndrome can be associated with aggressive non-testicular malignancies, especially uterine cancer, in normally virilized males.
Entities:
Keywords:
Anomalías congénitas urogenitales; Carcinoma clearzzm321990renal cells; Cáncer de endometrio; Cáncer de vejiga; Hematuria; Laparoscopic cystectomy; Simple renal cysts; Síndrome de persistencia del Conducto de Müller