Literature DB >> 31069504

Sample path properties of the average generation of a Bellman-Harris process.

Gianfelice Meli1, Tom S Weber2, Ken R Duffy3.   

Abstract

Motivated by a recently proposed design for a DNA coded randomised algorithm that enables inference of the average generation of a collection of cells descendent from a common progenitor, here we establish strong convergence properties for the average generation of a super-critical Bellman-Harris process. We further extend those results to a two-type Bellman-Harris process where one type can give rise to the other, but not vice versa. These results further affirm the estimation method's potential utility by establishing its long run accuracy on individual sample-paths, and significantly expanding its remit to encompass cellular development that gives rise to differentiated offspring with distinct population dynamics.

Keywords:  Average generation inference; Average tree depth inference; Bellman–Harris process; DNA coded algorithm; Sample-path properties; Two-type process

Mesh:

Year:  2019        PMID: 31069504     DOI: 10.1007/s00285-019-01373-0

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.259


  51 in total

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Journal:  Nat Genet       Date:  1997-12       Impact factor: 38.330

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Journal:  Nature       Date:  2016-10-17       Impact factor: 49.962

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