Literature DB >> 31068410

Initiation and Titration of Basal Insulin in Primary Care: Barriers and Practical Solutions.

Leigh Perreault1, Lauren Vincent2, Joshua J Neumiller2, Tricia Santos-Cavaiola2.   

Abstract

Basal insulin therapy is a critical part of effective type 2 diabetes (T2D) management for many patients, yet its initiation and titration are often delayed or avoided. Aversion to basal insulin therapy contributes to unnecessary hyperglycemia and poorer outcomes for patients. Primary care physicians often make decisions regarding the initiation of basal insulin in T2D, as they work closely with patients and are well placed to discuss and manage the transition to basal insulin therapy. However, many primary care clinicians hesitate to initiate basal insulin due to concerns regarding time or effort needed to educate patients, doubts about patient acceptance or ability to manage titration or injection, or patient fears of hypoglycemia. Resistance to basal insulin therapy is often linked to the outdated perception that the need for insulin represents a failure to control the disease, or that insulin is dangerous or toxic. Time concerns can be addressed via group classes and mobile technology and by working with diabetes educators in the community. Hypoglycemia or weight gain can be minimized with proper titration and use of second-generation basal insulins. This article reviews strategies for the initiation of basal insulin therapy, with an emphasis on the characteristics and titration of second-generation basal insulins, introducing current guidelines and offering suggestions for recognizing and overcoming barriers to insulin therapy in the management of T2D. © Copyright 2019 by the American Board of Family Medicine.

Entities:  

Keywords:  Hyperglycemia; Hypoglycemia; Insulin; Primary Care Physicians; Primary Health Care; Type 2 Diabetes Mellitus; Weight Gain

Mesh:

Substances:

Year:  2019        PMID: 31068410     DOI: 10.3122/jabfm.2019.03.180162

Source DB:  PubMed          Journal:  J Am Board Fam Med        ISSN: 1557-2625            Impact factor:   2.657


  9 in total

1.  [Short-term intensive combined therapy with metformin, sagliptin and dapagliflozin for newly diagnosed type 2 diabetes: efficacy, weight control and safety].

Authors:  Yufeng Xu; Peili Wu; Weiheng Wen; Hong Chen
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2019-11-30

2.  Evaluation of Clinical Outcomes With the V-Go Wearable Insulin Delivery Device in Patients With Type 2 Diabetes.

Authors:  Lisa T Meade; Dawn Battise
Journal:  Clin Diabetes       Date:  2021-07

3.  Impact of a Provider Tele-mentoring Learning Model on the Care of Medicaid-enrolled Patients With Diabetes.

Authors:  Joel C Cantor; Sujoy Chakravarty; Jennifer Farnham; Jose Nova; Sana Ahmad; James H Flory
Journal:  Med Care       Date:  2022-02-22       Impact factor: 3.178

Review 4.  Glargine-300: An updated literature review on randomized controlled trials and real-world studies.

Authors:  Sujoy Ghosh; Romik Ghosh
Journal:  World J Diabetes       Date:  2020-04-15

5.  Delphi-Based Consensus on Treatment Intensification in Type 2 Diabetes Subjects Failing Basal Insulin Supported Oral Treatment: Focus on Basal Insulin + GLP-1 Receptor Agonist Combination Therapies.

Authors:  Gian Paolo Fadini; Olga Disoteo; Riccardo Candido; Paolo Di Bartolo; Luigi Laviola; Agostino Consoli
Journal:  Diabetes Ther       Date:  2021-02-07       Impact factor: 2.945

6.  Pattern of Disease and Therapy for Diabetes along with Impact of Generic Prescribing on Cost of Treatment among Outpatients at a Tertiary Care Facility.

Authors:  Shubham Atal; Rajnish Joshi; Sadasivam Balakrishnan; Pooja Singh; Zeenat Fatima; Nidhi Jain
Journal:  J Pharm Bioallied Sci       Date:  2020-12-16

7.  Post Hoc Analysis Evaluating the Impact of Antihyperglycemic Background Therapies on Attainment of A1C Targets Without Hypoglycemia in the ACHIEVE Control Pragmatic, Real-Life Study.

Authors:  Timothy S Bailey; Pierre Evenou; Jasvinder Gill; Paulos Berhanu; Romain Raymond; Jodi Strong; Eugene E Wright
Journal:  Diabetes Spectr       Date:  2021-08-10

Review 8.  A practical approach to the clinical challenges in initiation of basal insulin therapy in people with type 2 diabetes.

Authors:  Thomas Forst; Pratik Choudhary; Doron Schneider; Bruno Linetzky; Paolo Pozzilli
Journal:  Diabetes Metab Res Rev       Date:  2020-12-01       Impact factor: 4.876

Review 9.  Current State and Principles of Basal Insulin Therapy in Type 2 Diabetes.

Authors:  Hernando Vargas-Uricoechea
Journal:  J Clin Med Res       Date:  2022-01-29
  9 in total

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