Literature DB >> 31067443

New Insights into the Regulation of Leptin Gene Expression.

Heike Münzberg1, Steven B Heymsfield2.   

Abstract

Leptin is a key hormone in the homeostatic regulation of body weight. While past research focused mainly on overall leptin actions, a recent study by Dallner et al. (2019) takes a fresh look at the regulatory elements of the leptin gene locus, providing new insights into processes that modulate leptin levels.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31067443      PMCID: PMC7346278          DOI: 10.1016/j.cmet.2019.04.005

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  15 in total

Review 1.  Central nervous system control of food intake.

Authors:  M W Schwartz; S C Woods; D Porte; R J Seeley; D G Baskin
Journal:  Nature       Date:  2000-04-06       Impact factor: 49.962

2.  The full expression of fasting-induced torpor requires beta 3-adrenergic receptor signaling.

Authors:  Steven J Swoap; Margaret J Gutilla; L Cameron Liles; Ross O Smith; David Weinshenker
Journal:  J Neurosci       Date:  2006-01-04       Impact factor: 6.167

Review 3.  Mechanisms of leptin action and leptin resistance.

Authors:  Martin G Myers; Michael A Cowley; Heike Münzberg
Journal:  Annu Rev Physiol       Date:  2008       Impact factor: 19.318

4.  Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor.

Authors:  M M Mason; Y He; H Chen; M J Quon; M Reitman
Journal:  Endocrinology       Date:  1998-03       Impact factor: 4.736

5.  Response of leptin to short-term and prolonged overfeeding in humans.

Authors:  J W Kolaczynski; J P Ohannesian; R V Considine; C C Marco; J F Caro
Journal:  J Clin Endocrinol Metab       Date:  1996-11       Impact factor: 5.958

6.  Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity.

Authors:  Olof S Dallner; Jill M Marinis; Yi-Hsueh Lu; Kivanc Birsoy; Emory Werner; Gulya Fayzikhodjaeva; Brian D Dill; Henrik Molina; Arden Moscati; Zoltán Kutalik; Pedro Marques-Vidal; Tuomas O Kilpeläinen; Niels Grarup; Allan Linneberg; Yinxin Zhang; Roger Vaughan; Ruth J F Loos; Mitchell A Lazar; Jeffrey M Friedman
Journal:  Nat Med       Date:  2019-03-06       Impact factor: 53.440

7.  Norepinephrine is required for leptin effects on gene expression in brown and white adipose tissue.

Authors:  S P Commins; D J Marsh; S A Thomas; P M Watson; M A Padgett; R Palmiter; T W Gettys
Journal:  Endocrinology       Date:  1999-10       Impact factor: 4.736

Review 8.  Structure, production and signaling of leptin.

Authors:  Heike Münzberg; Christopher D Morrison
Journal:  Metabolism       Date:  2014-09-28       Impact factor: 8.694

9.  Effects of the obese gene product on body weight regulation in ob/ob mice.

Authors:  M A Pelleymounter; M J Cullen; M B Baker; R Hecht; D Winters; T Boone; F Collins
Journal:  Science       Date:  1995-07-28       Impact factor: 47.728

10.  POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels.

Authors:  Alexandre Caron; Heather M Dungan Lemko; Carlos M Castorena; Teppei Fujikawa; Syann Lee; Caleb C Lord; Newaz Ahmed; Charlotte E Lee; William L Holland; Chen Liu; Joel K Elmquist
Journal:  Elife       Date:  2018-03-12       Impact factor: 8.140

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  3 in total

Review 1.  Leptin and psychiatric illnesses: does leptin play a role in antipsychotic-induced weight gain?

Authors:  Francky Teddy Endomba; Aurel T Tankeu; Jan René Nkeck; Joel Noutakdie Tochie
Journal:  Lipids Health Dis       Date:  2020-02-07       Impact factor: 3.876

2.  Leptin Methylation and mRNA Expression Associated With Psychopathology in Schizophrenia Inpatients.

Authors:  Jiaqi Song; Yan Chen; Qing Zhao; Hongna Li; Wei Li; Ke Chen; Jianjin Yu; Weihong Fu; Dachun Chen
Journal:  Front Psychiatry       Date:  2022-02-07       Impact factor: 4.157

3.  Spinal Cord Injury Reduces Serum Levels of Fibroblast Growth Factor-21 and Impairs Its Signaling Pathways in Liver and Adipose Tissue in Mice.

Authors:  Xin-Hua Liu; Zachary A Graham; Lauren Harlow; Jiangping Pan; Daniella Azulai; William A Bauman; Joshua Yarrow; Christopher P Cardozo
Journal:  Front Endocrinol (Lausanne)       Date:  2021-05-11       Impact factor: 5.555

  3 in total

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