Literature DB >> 31065884

Interventions to Reduce Ethnic and Racial Disparities in Dyslipidemia Management.

Andrew Y Chang1, Nadeem E Abou-Arraj2, Fatima Rodriguez3.   

Abstract

PURPOSE OF REVIEW: Race and ethnicity are associated with disparities in risk assessment, screening, patient awareness, treatment, and control of dyslipidemia and can contribute to worsened cardiovascular outcomes. This review summarizes these gaps in care and highlights recent interventions aimed at reducing them. RECENT
FINDINGS: Disparities in dyslipidemia diagnosis and treatment are well documented among certain racial and ethnic minority groups. Less is known about dyslipidemia among Hispanics, Asians, and Native Americans/Pacific Islanders, who have significant heterogeneity in cardiovascular risk and outcomes. Programs to reduce inequalities have focused on targeted risk assessment, improved screening practices, statin adherence-enhancing policies, culturally inclusive risk factor modification campaigns, and multidisciplinary treatment teams, with variable success. Interventions to reduce racial/ethnic disparities in dyslipidemia are important at all phases of care. Nevertheless, initiatives concentrating on single elements of the lipid treatment cascade were generally less effective at improving clinical endpoints than those that comprehensively addressed multiple phases. Moreover, there was a disproportionately greater number of published studies analyzing patient-facing lifestyle-based risk factor modifications than other types of interventions. Future investigations should focus on understudied populations such as disaggregated Hispanic, Asian, and Native American populations. Additionally, innovative strategies utilizing information technology and provider-facing programs are needed.

Entities:  

Keywords:  Community health; Dyslipidemia; Health disparities; Racial/ethnic differences in health care; Risk factor modification; Statins

Year:  2019        PMID: 31065884     DOI: 10.1007/s11936-019-0725-4

Source DB:  PubMed          Journal:  Curr Treat Options Cardiovasc Med        ISSN: 1092-8464


  67 in total

1.  Disparities in the diagnosis and pharmacologic treatment of high serum cholesterol by race and ethnicity: data from the Third National Health and Nutrition Examination Survey.

Authors:  Karin Nelson; Keith Norris; Carol M Mangione
Journal:  Arch Intern Med       Date:  2002-04-22

Review 2.  Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.

Authors:  Kiman Kim; Julie A Johnson; Hartmut Derendorf
Journal:  J Clin Pharmacol       Date:  2004-10       Impact factor: 3.126

Review 3.  Safety and efficacy of statins in Asians.

Authors:  James K Liao
Journal:  Am J Cardiol       Date:  2006-12-15       Impact factor: 2.778

Review 4.  Cardiovascular health disparities: a systematic review of health care interventions.

Authors:  Andrew M Davis; Lisa M Vinci; Tochi M Okwuosa; Ayana R Chase; Elbert S Huang
Journal:  Med Care Res Rev       Date:  2007-10       Impact factor: 3.929

5.  Increased prevalence of smaller and denser LDL particles in Asian Indians.

Authors:  K R Kulkarni; J H Markovitz; N C Nanda; J P Segrest
Journal:  Arterioscler Thromb Vasc Biol       Date:  1999-11       Impact factor: 8.311

6.  Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment.

Authors:  Edmund Lee; Stephen Ryan; Bruce Birmingham; Julie Zalikowski; Ruth March; Helen Ambrose; Rachael Moore; Caroline Lee; Yusong Chen; Dennis Schneck
Journal:  Clin Pharmacol Ther       Date:  2005-10       Impact factor: 6.875

Review 7.  Cardiometabolic health disparities in native Hawaiians and other Pacific Islanders.

Authors:  Marjorie K Mau; Ka'imi Sinclair; Erin P Saito; Kau'i N Baumhofer; Joseph Keawe'aimoku Kaholokula
Journal:  Epidemiol Rev       Date:  2009-06-16       Impact factor: 6.222

8.  Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2.

Authors:  Julia Hippisley-Cox; Carol Coupland; Yana Vinogradova; John Robson; Rubin Minhas; Aziz Sheikh; Peter Brindle
Journal:  BMJ       Date:  2008-06-23

9.  Dyslipidemia and the treatment of lipid disorders in African Americans.

Authors:  Herman A Taylor; Ermeg L Akylbekova; Robert J Garrison; Daniel Sarpong; Jennifer Joe; Evelyn Walker; Sharon B Wyatt; Michael W Steffes
Journal:  Am J Med       Date:  2009-05       Impact factor: 4.965

Review 10.  Transporter pharmacogenetics and statin toxicity.

Authors:  M Niemi
Journal:  Clin Pharmacol Ther       Date:  2009-11-04       Impact factor: 6.875

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  2 in total

1.  Statin usage and cardiovascular risk among people living with HIV in the U.S. Military HIV Natural History Study.

Authors:  Derek Larson; Seung Hyun Won; Anuradha Ganesan; Ryan C Maves; Karl Kronmann; Jason F Okulicz; Xiuping Chu; Christina Schofield; Thomas O'Bryan; Brian K Agan; Robert Deiss
Journal:  HIV Med       Date:  2021-10-26       Impact factor: 3.180

Review 2.  Unique Cardiovascular Disease Risk Factors in Hispanic Individuals.

Authors:  Sofia Gomez; Vanessa Blumer; Fatima Rodriguez
Journal:  Curr Cardiovasc Risk Rep       Date:  2022-06-02
  2 in total

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