S Behnke1. 1. Klinik für Neurologie, Universitätskliniken des Saarlandes, Kirrberger Str., 66421, Homburg Saar, Deutschland. stefanie.behnke@uks.eu.
Abstract
BACKGROUND: Thrombolysis with recombinant tissue plasminogen activator (rt-PA) and interventional thrombectomy are evidence-based causative therapies in acute stroke; however, the clinical benefit for the patient has been proven to be highly time-dependent. METHODS: A review of critical time intervals in acute stroke management and possibilities for modification is presented. RESULTS: Both prehospital and in-hospital times can be reduced with proven clinical benefits. The means to achieve time reductions are diverse and require clear workflow guidelines and continuous training. CONCLUSION: Optimization of time management during the complete acute diagnostics and treatment procedure by avoiding specific delays and streamlining universal workflow is of utmost importance regarding the efficiency and safety of treatment.
BACKGROUND: Thrombolysis with recombinant tissue plasminogen activator (rt-PA) and interventional thrombectomy are evidence-based causative therapies in acute stroke; however, the clinical benefit for the patient has been proven to be highly time-dependent. METHODS: A review of critical time intervals in acute stroke management and possibilities for modification is presented. RESULTS: Both prehospital and in-hospital times can be reduced with proven clinical benefits. The means to achieve time reductions are diverse and require clear workflow guidelines and continuous training. CONCLUSION: Optimization of time management during the complete acute diagnostics and treatment procedure by avoiding specific delays and streamlining universal workflow is of utmost importance regarding the efficiency and safety of treatment.
Authors: Karin Rossnagel; Gerhard Jan Jungehülsing; Christian H Nolte; Jacqueline Müller-Nordhorn; Stephanie Roll; Karl Wegscheider; Arno Villringer; Stefan N Willich Journal: Ann Emerg Med Date: 2004-11 Impact factor: 5.721
Authors: Brian H Buck; Sidney Starkman; Marc Eckstein; Chelsea S Kidwell; Jill Haines; Rainy Huang; Daniel Colby; Jeffrey L Saver Journal: Stroke Date: 2009-04-23 Impact factor: 7.914