Literature DB >> 31065181

Study of pain response in neonates during venipuncture with a view to analyse utility of topical anaesthetic agent for alleviating pain.

Hardeep Kaur1, Vandana Negi2, Mukti Sharma3, Gaurav Mahajan4.   

Abstract

BACKGROUND: Neonates being nonverbal are unable to express their pain leading to underestimation of their pain and hence insufficient pain relief. Neonatal pain is assessed by pain scales based on the behavioural and physiological changes that occur in response to painful stimuli. This cross sectional study was conducted at a tertiary care centre using Premature Infant Pain Profile (PIPP) score with 4% lidocaine as local anaesthetic agent to produce surface anaesthesia of skin prior to intravenous cannulation.
METHODS: Sample size was collected by simple randomisation method. Our study groups included 50 term and 50 preterm neonates with POG of 28-40 weeks requiring IV cannulation. Heart rate (HR), SpO2, facial expressions and behavioural state were noted before venipuncture and after venipuncture using PIPP scale. Same cohort of patients was assessed for pain response after applying 4% lidocaine cream during future venipuncture with help of PIPP score.
RESULTS: The PIPP score in preterm group before and after anesthesia was 11.28 ± 3.72 and 9.58 ± 3.39. PIPP score in term group before and after anesthesia was 11.54 ± 2.84 and 9.04 ± 2.97. There was reduction in mean PIPP score after using topical anesthetic agent in both study groups and the results were statistically significant.
CONCLUSION: This study found that topical anesthetic agents were effective in reducing pain during venipuncture. Based on the facts of the study, it is recommended that pain scoring should be a part of routine monitoring in neonatal intensive care units and appropriate measures should be used to reduce pain.

Entities:  

Keywords:  Low birth weight; New Ballard Score; Period of gestation; Premature Infant Pain Profile; Topical anaesthesia

Year:  2018        PMID: 31065181      PMCID: PMC6495100          DOI: 10.1016/j.mjafi.2017.12.009

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  16 in total

1.  Pain, plasticity, and premature birth: a prescription for permanent suffering?

Authors:  K J Anand
Journal:  Nat Med       Date:  2000-09       Impact factor: 53.440

2.  A randomized trial of eutectic mixture of local anesthetics during lumbar puncture in newborns.

Authors:  Geetinder Kaur; Piyush Gupta; Ashok Kumar
Journal:  Arch Pediatr Adolesc Med       Date:  2003-11

3.  Pain terms: a list with definitions and notes on usage. Recommended by the IASP Subcommittee on Taxonomy.

Authors: 
Journal:  Pain       Date:  1979-06       Impact factor: 6.961

Review 4.  Assessment and management of acute pain in high-risk neonates.

Authors:  Sharyn Gibbins; Bonnie Stevens; Elizabeth Asztalos
Journal:  Expert Opin Pharmacother       Date:  2003-04       Impact factor: 3.889

Review 5.  Topical anaesthesia for needle-related pain in newborn infants.

Authors:  Jann P Foster; Christine Taylor; Kaye Spence
Journal:  Cochrane Database Syst Rev       Date:  2017-02-04

Review 6.  Consensus statement for the prevention and management of pain in the newborn.

Authors:  K J Anand
Journal:  Arch Pediatr Adolesc Med       Date:  2001-02

7.  Randomized trial of novel tetracaine patch to provide local anaesthesia in neonates undergoing venepuncture.

Authors:  C P Long; D F McCafferty; N M Sittlington; H L Halliday; A D Woolfson; D S Jones
Journal:  Br J Anaesth       Date:  2003-10       Impact factor: 9.166

Review 8.  Pain management in nursing procedures on premature babies.

Authors:  Sirkka-Liisa Halimaa
Journal:  J Adv Nurs       Date:  2003-06       Impact factor: 3.187

9.  Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates.

Authors:  Sinno H P Simons; Monique van Dijk; Kanwaljeet S Anand; Daniella Roofthooft; Richard A van Lingen; Dick Tibboel
Journal:  Arch Pediatr Adolesc Med       Date:  2003-11

10.  Pain expression in neonates: facial action and cry.

Authors:  Ruth V E Grunau; Kenneth D Craig
Journal:  Pain       Date:  1987-03       Impact factor: 6.961

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  1 in total

Review 1.  Early Neonatal Pain-A Review of Clinical and Experimental Implications on Painful Conditions Later in Life.

Authors:  Morika D Williams; B Duncan X Lascelles
Journal:  Front Pediatr       Date:  2020-02-07       Impact factor: 3.418

  1 in total

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