Literature DB >> 31064545

Why replication has more scientific value than original discovery.

John P A Ioannidis1.   

Abstract

The presumed dominance of "original discovery" over replication is an anomaly. Original discovery has more value than replication primarily when scientific investigation can immediately generate numerous discoveries most of which are true and accurate. This scenario is uncommon. A model shows how original discovery claims typically have small or even negative value. Science becomes worthy mostly because of replication.

Entities:  

Year:  2018        PMID: 31064545     DOI: 10.1017/S0140525X18000729

Source DB:  PubMed          Journal:  Behav Brain Sci        ISSN: 0140-525X            Impact factor:   12.579


  7 in total

1.  How to find a meta-analysis you can trust.

Authors:  R L Nelson
Journal:  Tech Coloproctol       Date:  2019-08-28       Impact factor: 3.781

2.  Editorial: Replication and Reliability in Behavior Science and Behavior Analysis: A Call for a Conversation.

Authors:  Donald A Hantula
Journal:  Perspect Behav Sci       Date:  2019-03-11

3.  Residential neighborhood features associated with objectively measured walking near home: Revisiting walkability using the Automatic Context Measurement Tool (ACMT).

Authors:  Stephen J Mooney; Philip M Hurvitz; Anne Vernez Moudon; Chuan Zhou; Ronit Dalmat; Brian E Saelens
Journal:  Health Place       Date:  2020-04-24       Impact factor: 4.078

4.  Current Status and Future Opportunities in Modeling Clinical Characteristics of Multiple Sclerosis.

Authors:  Joshua Liu; Erin Kelly; Bibiana Bielekova
Journal:  Front Neurol       Date:  2022-05-27       Impact factor: 4.086

5.  Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD).

Authors:  Christina Kiel; Tobias Strunz; Felix Grassmann; Bernhard H F Weber
Journal:  Cells       Date:  2020-10-08       Impact factor: 6.600

6.  Sexual trauma uniquely associated with eating disorders: A replication study.

Authors:  Francesca Gomez; Lisa Smith Kilpela; Keesha M Middlemass; Carolyn Black Becker
Journal:  Psychol Trauma       Date:  2020-09-17

7.  A generic outcome assessment of mobility capacity in neurorehabilitation: measurement properties of the de Morton Mobility Index.

Authors:  Tobias Braun; Detlef Marks; Christian Thiel; Christian Grüneberg
Journal:  BMC Neurol       Date:  2021-07-28       Impact factor: 2.474

  7 in total

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