| Literature DB >> 31063746 |
Abstract
Overcoming intrinsic and extrinsic tumor-suppressive barriers is an essential feature of tumor progression. In this issue of Developmental Cell, Michael et al. (2019) use the RIP-Tag mouse model to show that pro-apoptotic signals mediated by the Activin B-ALK7 axis suppress ectopic proliferation and metastasis during pancreatic neuroendocrine cancer development.Entities:
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Year: 2019 PMID： 31063746 DOI： 10.1016/j.devcel.2019.04.025
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270