Literature DB >> 3106303

Susceptibility of Rickettsia conorii and R. rickettsii to pefloxacin, in vitro and in ovo.

D Raoult, P Roussellier, G Vestris, V Galicher, R Perez, J Tamalet.   

Abstract

The activity of pefloxacin against Rickettsia conorii and R. rickettsii was determined by several methods. The mean survival time of embryonated eggs infected with R. conorii was increased by pefloxacin 50 micrograms/egg; plaque formation in Vero cells was inhibited by 1 mg/l. In a microplate assay, the MIC of pefloxacin was 0.5 mg/l for R. conorii and 1 mg/l for R. rickettsii. The results support the use of pefloxacin in treating spotted fever rickettsioses.

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Year:  1987        PMID： 3106303     DOI： 10.1093/jac/19.3.303

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  9 in total

Review 1.  Antimicrobial therapy of rickettsial diseases.

Authors:  D Raoult; M Drancourt
Journal:  Antimicrob Agents Chemother       Date:  1991-12       Impact factor: 5.191

2.  Antibiotic susceptibility of rickettsia and treatment of rickettsioses.

Authors:  D Raoult
Journal:  Eur J Epidemiol       Date:  1989-12       Impact factor: 8.082

3.  In vitro susceptibilities of Rickettsia rickettsii and Rickettsia conorii to roxithromycin and pristinamycin.

Authors:  M Drancourt; D Raoult
Journal:  Antimicrob Agents Chemother       Date:  1989-12       Impact factor: 5.191

Review 4.  Antibiotic treatment of rickettsiosis, recent advances and current concepts.

Authors:  D Raoult
Journal:  Eur J Epidemiol       Date:  1991-05       Impact factor: 8.082

5.  In vitro susceptibilities of Coxiella burnetii, Rickettsia rickettsii, and Rickettsia conorii to the fluoroquinolone sparfloxacin.

Authors:  D Raoult; P Bres; M Drancourt; G Vestris
Journal:  Antimicrob Agents Chemother       Date:  1991-01       Impact factor: 5.191

Review 6.  A comparative view of Rickettsia tsutsugamushi and the other groups of rickettsiae.

Authors:  A Tamura; H Urakami; N Ohashi
Journal:  Eur J Epidemiol       Date:  1991-05       Impact factor: 8.082

Review 7.  Fluoroquinolone antimicrobial agents.

Authors:  J S Wolfson; D C Hooper
Journal:  Clin Microbiol Rev       Date:  1989-10       Impact factor: 26.132

8.  In vitro evaluation of josamycin, spiramycin, and erythromycin against Rickettsia rickettsii and R. conorii.

Authors:  D Raoult; P Roussellier; J Tamalet
Journal:  Antimicrob Agents Chemother       Date:  1988-02       Impact factor: 5.191

Review 9.  Epidemiology, Clinical Aspects, Laboratory Diagnosis and Treatment of Rickettsial Diseases in the Mediterranean Area During COVID-19 Pandemic: A Review of the Literature.

Authors:  Andrea De Vito; Nicholas Geremia; Sabrina Maria Mameli; Vito Fiore; Pier Andrea Serra; Gaia Rocchitta; Susanna Nuvoli; Angela Spanu; Renato Lobrano; Antonio Cossu; Sergio Babudieri; Giordano Madeddu
Journal:  Mediterr J Hematol Infect Dis       Date:  2020-09-01       Impact factor: 2.576
  9 in total

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