Literature DB >> 3106224

Growth inhibition of Trypanosoma cruzi in cultured murine myocardial cells mediated by a specifically induced lymphokine.

L Reyes, M Chinchilla.   

Abstract

An in vitro model for studying the protection of mouse myocardial cells against Trypanosoma cruzi was developed. It was demonstrated that immune mouse lymphocytes stimulated with a specific antigen elicited a mediator which protected myocardial cells from newborn mice against T. cruzi infection. The substance responsible for this activity was sensitive to acid (pH 2) treatment.

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Year:  1987        PMID: 3106224      PMCID: PMC260544          DOI: 10.1128/iai.55.6.1513-1516.1987

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  12 in total

1.  Production and properties of migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity.

Authors:  J S Youngner; S B Salvin
Journal:  J Immunol       Date:  1973-12       Impact factor: 5.422

2.  Specific mediation of cellular immunity to Toxoplasma gondii in somatic cells of mice.

Authors:  M Chinchilla; J K Frenkel
Journal:  Infect Immun       Date:  1984-12       Impact factor: 3.441

3.  Mediation of immunity to intracellular infection (Toxoplasma and Besnoitia) within somatic cells.

Authors:  M Chinchilla; J K Frenkel
Journal:  Infect Immun       Date:  1978-03       Impact factor: 3.441

4.  In vitro production of metacyclic trypomastigotes of Trypanosoma cruzi.

Authors:  D G Dusanic
Journal:  J Parasitol       Date:  1980-12       Impact factor: 1.276

5.  Inhibition of growth of Toxoplasma gondii in cultured fibroblasts by human recombinant gamma interferon.

Authors:  E R Pfefferkorn; P M Guyre
Journal:  Infect Immun       Date:  1984-05       Impact factor: 3.441

6.  Role of activated macrophages in resistance of mice to infection with Trypanosoma cruzi.

Authors:  D M Williams; S Sawyer; J S Remington
Journal:  J Infect Dis       Date:  1976-12       Impact factor: 5.226

7.  Interferon-gamma inhibits growth of Coxiella burnetii in mouse fibroblasts.

Authors:  J Turco; H A Thompson; H H Winkler
Journal:  Infect Immun       Date:  1984-09       Impact factor: 3.441

8.  Trypanosoma cruzi: protection in mice immunized with 8-methoxypsoralen-inactivated trypomastigotes.

Authors:  N W Andrews; M J Alves; R I Schumacher; W Colli
Journal:  Exp Parasitol       Date:  1985-12       Impact factor: 2.011

9.  Interferonlike factors from antigen- and mitogen-stimulated human leukocytes with antirickettsial and cytolytic actions on Rickettsia prowazekii. Infected human endothelial cells, fibroblasts, and macrophages.

Authors:  C L Wisseman; A Waddell
Journal:  J Exp Med       Date:  1983-06-01       Impact factor: 14.307

10.  Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo.

Authors:  R Hoff
Journal:  J Exp Med       Date:  1975-08-01       Impact factor: 14.307

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