Literature DB >> 31061588

How effective is periarticular drug infiltration in providing pain relief and early functional outcome following total hip arthroplasty?

George Mathew Srampickal1, Korula Mani Jacob1, Jacob Joe Kandoth1, Bijesh Kumar Yadev2, Tyagraj Palraj3, Anil Thomas Oommen1, Sajan Philip George4, Pradeep Mathew Poonnoose1.   

Abstract

The aim of the study was to compare the efficacy of periarticular injection of a cocktail of analgesic drugs (PIC) with epidural infiltration (EA), in providing postoperative pain relief and early functional improvement following Total Hip Arthroplasty (THA).
METHODS: 50 patients undergoing unilateral THA were randomized to receive either EA or PIC for postoperative pain control. Postoperative pain relief, as determined by the visual analogue scale (VAS), functional recovery and side effects related to EA and PIC were assessed.
RESULTS: PIC resulted in significantly lower VAS scores [0.48(0.71) vs 3.04(2.07)] in the first 24 h after surgery [mean (SD)], when compared to EA. The pain relief continued to be significantly lower even on the 10th postoperative day. Functional recovery was significantly better in the PIC group, with patients being able to walk longer distances and climb steps more quickly following THA. EA, unlike PIC was associated with side effects like nausea, vomiting, motor weakness, back pain and urinary retention. The overall satisfaction rate with treatment was significantly better in PIC group (9.04/10) than those who received EA (7.76/10).
CONCLUSION: PIC provides significantly better pain control and functional recovery in the early postoperative period, with less side effects when compared with EA. PIC should be the choice for pain control following THA.

Entities:  

Keywords:  Cocktail; Epidural infiltration; Pain; Periarticular injection; THR

Year:  2018        PMID: 31061588      PMCID: PMC6492212          DOI: 10.1016/j.jcot.2018.06.005

Source DB:  PubMed          Journal:  J Clin Orthop Trauma        ISSN: 0976-5662


  29 in total

1.  Pain management after total joint replacement and its impact on patient outcomes.

Authors:  T C Nussenzveig
Journal:  AORN J       Date:  1999-12       Impact factor: 0.676

Review 2.  Safety and efficacy of postoperative epidural analgesia.

Authors:  R G Wheatley; S A Schug; D Watson
Journal:  Br J Anaesth       Date:  2001-07       Impact factor: 9.166

Review 3.  Epidural analgesia for pain relief following hip or knee replacement.

Authors:  P T Choi; M Bhandari; J Scott; J Douketis
Journal:  Cochrane Database Syst Rev       Date:  2003

Review 4.  Pre-emptive analgesia.

Authors:  Jørgen B Dahl; Steen Møiniche
Journal:  Br Med Bull       Date:  2004-12-13       Impact factor: 4.291

5.  Mortality, morbidity, and 1-year outcomes of primary elective total hip arthroplasty.

Authors:  Olwen Williams; Ray Fitzpatrick; Shakoor Hajat; Barnaby C Reeves; Anne Stimpson; Richard W Morris; David W Murray; Marianne Rigge; Paul J Gregg
Journal:  J Arthroplasty       Date:  2002-02       Impact factor: 4.757

Review 6.  Current concepts and practice in postoperative pain management: need for a change?

Authors:  K S Filos; K A Lehmann
Journal:  Eur Surg Res       Date:  1999       Impact factor: 1.745

7.  Effects of perioperative analgesic technique on the surgical outcome and duration of rehabilitation after major knee surgery.

Authors:  X Capdevila; Y Barthelet; P Biboulet; Y Ryckwaert; J Rubenovitch; F d'Athis
Journal:  Anesthesiology       Date:  1999-07       Impact factor: 7.892

Review 8.  Non-opioid postoperative analgesia.

Authors:  V Dahl; J C Raeder
Journal:  Acta Anaesthesiol Scand       Date:  2000-11       Impact factor: 2.105

9.  Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.

Authors:  Harry B Skinner; Ellen Y Shintani
Journal:  Am J Orthop (Belle Mead NJ)       Date:  2004-02

10.  Chronic pain following total hip arthroplasty: a nationwide questionnaire study.

Authors:  L Nikolajsen; B Brandsborg; U Lucht; T S Jensen; H Kehlet
Journal:  Acta Anaesthesiol Scand       Date:  2006-04       Impact factor: 2.105

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  2 in total

1.  Peri-operative Morbidity Associated with Bilateral Hip Arthroplasty for Inflammatory Arthritis: Results from a Consecutive Series of 168 Hips.

Authors:  Rahul George; V J Chandy; A I Christudoss; T D Hariharan; A ArunShankar; B Antonisamy; A T Oommen; Pradeep Mathew Poonnoose
Journal:  Indian J Orthop       Date:  2021-08-09       Impact factor: 1.033

2.  Intraoperative periarticular injection can alleviate the inflammatory response and enhance joint function recovery after hip arthroplasty in elderly patients with osteoporotic femoral neck fractures.

Authors:  Zhizheng Xiong; Shuai Cao; Lingling Zhou; Xu Zhang; Qi Liu; Jinxi Hu; Fang Liu; Yongwei Li
Journal:  Medicine (Baltimore)       Date:  2021-02-19       Impact factor: 1.817

  2 in total

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