Literature DB >> 31061182

Successful thrombolysis for acute ischaemic stroke after reversal of dabigatran etexilate with idarucizumab.

Chee Hoou Loh1,2, Geoffrey Herkes1,2.   

Abstract

We report the experience of reversing dabigatran prior to administering systemic thrombolysis for acute ischaemic cerebellar stroke, which was well tolerated with no haemorrhagic complications after thrombolysis. Given the increasingly common use of dabigatran for atrial fibrillation, the use of idarucizumab to reverse of dabigatran is a novel treatment that should be considered as an important adjunct to facilitate thrombolysis for ischaemic strokes and minimise haemorrhagic complications. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  arrhythmias; haematology (drugs and medicines); neurology (drugs and medicines)

Mesh:

Substances:

Year:  2019        PMID: 31061182      PMCID: PMC6506077          DOI: 10.1136/bcr-2018-229128

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  21 in total

1.  Massive left atrial thrombus in a patient with rheumatic mitral stenosis and atrial fibrillation while anticoagulated with dabigatran.

Authors:  Sushil Allen Luis; Karl Poon; Chris Luis; Akhil Shukla; Nicholas Bett; Christian Hamilton-Craig
Journal:  Circ Cardiovasc Imaging       Date:  2013-05-01       Impact factor: 7.792

2.  2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

Authors:  Patrick T O'Gara; Frederick G Kushner; Deborah D Ascheim; Donald E Casey; Mina K Chung; James A de Lemos; Steven M Ettinger; James C Fang; Francis M Fesmire; Barry A Franklin; Christopher B Granger; Harlan M Krumholz; Jane A Linderbaum; David A Morrow; L Kristin Newby; Joseph P Ornato; Narith Ou; Martha J Radford; Jacqueline E Tamis-Holland; Carl L Tommaso; Cynthia M Tracy; Y Joseph Woo; David X Zhao; Jeffrey L Anderson; Alice K Jacobs; Jonathan L Halperin; Nancy M Albert; Ralph G Brindis; Mark A Creager; David DeMets; Robert A Guyton; Judith S Hochman; Richard J Kovacs; Frederick G Kushner; E Magnus Ohman; William G Stevenson; Clyde W Yancy
Journal:  Circulation       Date:  2012-12-17       Impact factor: 29.690

Review 3.  2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

Authors:  William J Powers; Alejandro A Rabinstein; Teri Ackerson; Opeolu M Adeoye; Nicholas C Bambakidis; Kyra Becker; José Biller; Michael Brown; Bart M Demaerschalk; Brian Hoh; Edward C Jauch; Chelsea S Kidwell; Thabele M Leslie-Mazwi; Bruce Ovbiagele; Phillip A Scott; Kevin N Sheth; Andrew M Southerland; Deborah V Summers; David L Tirschwell
Journal:  Stroke       Date:  2018-01-24       Impact factor: 7.914

4.  Dabigatran for left ventricular thrombus.

Authors:  Satishkumar Kolekar; Chandrashekhar Munjewar; Satyavan Sharma
Journal:  Indian Heart J       Date:  2015-08-08

Review 5.  Global epidemiology of atrial fibrillation.

Authors:  Faisal Rahman; Gene F Kwan; Emelia J Benjamin
Journal:  Nat Rev Cardiol       Date:  2014-08-12       Impact factor: 32.419

6.  Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.

Authors:  Walter N Kernan; Bruce Ovbiagele; Henry R Black; Dawn M Bravata; Marc I Chimowitz; Michael D Ezekowitz; Margaret C Fang; Marc Fisher; Karen L Furie; Donald V Heck; S Claiborne Clay Johnston; Scott E Kasner; Steven J Kittner; Pamela H Mitchell; Michael W Rich; DeJuran Richardson; Lee H Schwamm; John A Wilson
Journal:  Stroke       Date:  2014-05-01       Impact factor: 7.914

7.  Treatment of acute stroke in patients on dabigatran: a survey of US stroke specialists.

Authors:  Igor Rybinnik; Michael T Mullen; Steven Messe; Scott E Kasner; Brett Cucchiara
Journal:  J Stroke Cerebrovasc Dis       Date:  2013-01-10       Impact factor: 2.136

8.  Dabigatran Added to Dual Antiplatelet Therapy to Treat a Left Ventricular Thrombus in an 87 Year Old Patient With Myocardial Infarction and Very High Bleeding Risk.

Authors:  Maria Noflatscher; Nicolas Moes; Eva-Maria Gassner; Peter Marschang
Journal:  Front Pharmacol       Date:  2018-04-04       Impact factor: 5.810

9.  Dabigatran for left atrial thrombus.

Authors:  Sae Morita; Yoichi Ajiro; Yoshie Uchida; Kazunori Iwade
Journal:  Eur Heart J       Date:  2013-05-22       Impact factor: 29.983

10.  Large Left Ventricular Thrombus as a Cause of Recurrent Cardioembolic Stroke While on Dabigatran.

Authors:  Melissa Y Y Moey; Anna N Tomdio; Olisaemeka Achike; Deepa Kabirdas
Journal:  CASE (Phila)       Date:  2018-07-07
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  1 in total

1.  Intravenous Thrombolysis After Dabigatran Reversal by Idarucizumab: A Systematic Review of the Literature.

Authors:  Senta Frol; Dimitrios Sagris; Janja Pretnar Oblak; Mišo Šabovič; George Ntaios
Journal:  Front Neurol       Date:  2021-06-03       Impact factor: 4.003

  1 in total

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