| Literature DB >> 31057198 |
Yi Hong Ong1,2, Andrew Q Li1, Timothy C Zhu1.
Abstract
In this study, we use Monte Carlo modelling to investigate the effect of tissue optical properties on Cherenkov emission detected from tissue surface. MC simulations are performed for wavelength between 400-1000nm and the values of absorption coefficient at each wavelength are determined based on the molar extinction coefficients of oxy- and deoxy-hemoglobin, with varying total haemoglobin concentration and tissue oxygen saturation of 70%. Tissue reduced scattering coefficient is approximated using μs'(λ) = Aλ-0.838. A range of clinically relevant tissue optical properties was investigated, with absorption coefficient between 0.1 and 1 cm-1 and reduced scattering coefficient between 5 and 40 cm-1 at 665nm. The angular distribution, depth of origins and the effect of tissue optical properties on Cherenkov emission on tissue surface are evaluated.Entities:
Keywords: Cherenkov emission; MC simulation; angular distribution; depth of origins; light propagation; tissue optical properties; total skin electron beam therapy
Year: 2019 PMID： 31057198 PMCID： PMC6497392 DOI： 10.1117/12.2509854
Source DB: PubMed Journal: Proc SPIE Int Soc Opt Eng ISSN： 0277-786X