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Literature DB >> 3105474

Spironolactone in the treatment of hirsutism.

Abstract

Spironolactone was used in 90 hirsute women because of its antiandrogenic effect. The drug was administered twice daily from the 4th to the 22nd day of six cycles (total dosage was 200 mg per day). The results suggest that spironolactone is suitable for the treatment of hirsutism.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1987 PMID： 3105474 DOI： 10.1007/bf02134041

Source DB: PubMed Journal: Arch Gynecol ISSN： 0170-9925

17 in total

1. URINARY STEROID EXCRETION PATTERNS IN HIRSUTISM. I. USE OF ADRENAL AND OVARIAN SUPPRESSION TESTS IN THE STUDY OF HIRSUTISM.

Authors: V B MAHESH; R B GREENBLATT; C K AYDAR; S ROY; R A PUEBLA; J O ELLEGOOD
Journal: J Clin Endocrinol Metab Date: 1964-12 Impact factor: 5.958

2. Spironolactone and testicular cytochrome P-450: decreased testosterone formation in several species and changes in hepatic drug metabolism.

Authors: R H Menard; B Stripp; J R Gillette
Journal: Endocrinology Date: 1974-06 Impact factor: 4.736

Spironolactone in the treatment of hirsutism.

1. URINARY STEROID EXCRETION PATTERNS IN HIRSUTISM. I. USE OF ADRENAL AND OVARIAN SUPPRESSION TESTS IN THE STUDY OF HIRSUTISM.

2. Spironolactone and testicular cytochrome P-450: decreased testosterone formation in several species and changes in hepatic drug metabolism.

3. Plasma androgens in patients with the polycystic overy syndrome.

4. Effect of estrogen administration on androgen production and plasma luteinizing hormone in hirsute women.

5. Spironolactone therapy for hirsutism in a hyperandrogenic woman.

6. Treatment of hirsutism with spironolactone.

7. Therapeutic effects of spironolactone in polycystic ovary syndrome.

8. Interaction of digitalis and spironolactone with human sex steroid receptors.

9. A novel use of spironolactone: treatment of hirsutism.

10. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women.

Review 1. Hirsutism and the effectiveness of spironolactone in its management.