Literature DB >> 31053347

Cysteine and hydrophobic residues in CDR3 serve as distinct T-cell self-reactivity indices.

Stephen R Daley1, Hui-Fern Koay2, Kerry Dobbs3, Marita Bosticardo3, Rushika C Wirasinha4, Francesca Pala3, Riccardo Castagnoli3, Jared H Rowe5, Lisa M Ott de Bruin6, Sevgi Keles7, Yu Nee Lee8, Raz Somech8, Steven M Holland3, Ottavia M Delmonte3, Debbie Draper3, Sandra Maxwell3, Julie Niemela9, Jennifer Stoddard9, Sergio D Rosenzweig9, Pietro Luigi Poliani10, Valentina Capo11, Anna Villa12, Dale I Godfrey2, Luigi D Notarangelo13.   

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Year:  2019        PMID： 31053347      PMCID： PMC6675456          DOI： 10.1016/j.jaci.2019.03.022

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   10.793


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  9 in total

Review 1.  RAG gene defects at the verge of immunodeficiency and immune dysregulation.

Authors:  Anna Villa; Luigi D Notarangelo
Journal:  Immunol Rev       Date:  2019-01       Impact factor: 12.988

2.  αβ T-cell receptors with a central CDR3 cysteine are enriched in CD8αα intraepithelial lymphocytes and their thymic precursors.

Authors:  Rushika C Wirasinha; Mandeep Singh; Stuart K Archer; Anna Chan; Paul F Harrison; Christopher C Goodnow; Stephen R Daley
Journal:  Immunol Cell Biol       Date:  2018-05-03       Impact factor: 5.126

3.  The checkpoint for agonist selection precedes conventional selection in human thymus.

Authors:  Greet Verstichel; David Vermijlen; Liesbet Martens; Glenn Goetgeluk; Margreet Brouwer; Nicolas Thiault; Yasmine Van Caeneghem; Stijn De Munter; Karin Weening; Sarah Bonte; Georges Leclercq; Tom Taghon; Tessa Kerre; Yvan Saeys; Jo Van Dorpe; Hilde Cheroutre; Bart Vandekerckhove
Journal:  Sci Immunol       Date:  2017-02-24

4.  Recombination activity of human recombination-activating gene 2 (RAG2) mutations and correlation with clinical phenotype.

Authors:  Irit Tirosh; Yasuhiro Yamazaki; Francesco Frugoni; Francesca A Ververs; Eric J Allenspach; Yu Zhang; Siobhan Burns; Waleed Al-Herz; Lenora Noroski; Jolan E Walter; Andrew R Gennery; Mirjam van der Burg; Luigi D Notarangelo; Yu Nee Lee
Journal:  J Allergy Clin Immunol       Date:  2018-06-18       Impact factor: 10.793

5.  Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment.

Authors:  D B Klug; C Carter; E Crouch; D Roop; C J Conti; E R Richie
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-29       Impact factor: 11.205

6.  Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome.

Authors:  Pietro Luigi Poliani; Fabio Facchetti; Maria Ravanini; Andrew Richard Gennery; Anna Villa; Chaim M Roifman; Luigi D Notarangelo
Journal:  Blood       Date:  2009-05-04       Impact factor: 22.113

7.  Developmental regulation of Foxp3 expression during ontogeny.

Authors:  Jason D Fontenot; James L Dooley; Andrew G Farr; Alexander Y Rudensky
Journal:  J Exp Med       Date:  2005-10-03       Impact factor: 14.307

8.  CD8αα intraepithelial lymphocytes arise from two main thymic precursors.

Authors:  Roland Ruscher; Rebecca L Kummer; You Jeong Lee; Stephen C Jameson; Kristin A Hogquist
Journal:  Nat Immunol       Date:  2017-05-22       Impact factor: 25.606

9.  Hydrophobic CDR3 residues promote the development of self-reactive T cells.

Authors:  Brian D Stadinski; Karthik Shekhar; Iria Gómez-Touriño; Jonathan Jung; Katsuhiro Sasaki; Andrew K Sewell; Mark Peakman; Arup K Chakraborty; Eric S Huseby
Journal:  Nat Immunol       Date:  2016-06-27       Impact factor: 25.606
  9 in total
  15 in total

Review 1.  Immune dysregulation in patients with RAG deficiency and other forms of combined immune deficiency.

Authors:  Ottavia M Delmonte; Anna Villa; Luigi D Notarangelo
Journal:  Blood       Date:  2020-02-27       Impact factor: 22.113

2.  SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation.

Authors:  Ottavia M Delmonte; Jenna R E Bergerson; Tomoki Kawai; Hye Sun Kuehn; David H McDermott; Irene Cortese; Michael T Zimmermann; A Kerry Dobbs; Marita Bosticardo; Danielle Fink; Shamik Majumdar; Boaz Palterer; Francesca Pala; Nikita R Dsouza; Marie Pouzolles; Naomi Taylor; Katherine R Calvo; Stephen R Daley; Daniel Velez; Anahita Agharahimi; Katherine Myint-Hpu; Lesia K Dropulic; Jonathan J Lyons; Steven M Holland; Alexandra F Freeman; Rajarshi Ghosh; Morgan B Similuk; Julie E Niemela; Jennifer Stoddard; Douglas B Kuhns; Raul Urrutia; Sergio D Rosenzweig; Magdalena A Walkiewicz; Philip M Murphy; Luigi D Notarangelo
Journal:  Blood       Date:  2021-09-23       Impact factor: 25.476

Review 3.  RAG deficiencies: Recent advances in disease pathogenesis and novel therapeutic approaches.

Authors:  Marita Bosticardo; Francesca Pala; Luigi D Notarangelo
Journal:  Eur J Immunol       Date:  2021-03-22       Impact factor: 6.688

4.  Human Thymic CD10+ PD-1+ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a- CD95+ CD28- CCR7- Developmental Stage.

Authors:  Lore Billiet; Glenn Goetgeluk; Sarah Bonte; Stijn De Munter; Laurenz De Cock; Melissa Pille; Joline Ingels; Hanne Jansen; Karin Weening; Filip Van Nieuwerburgh; Tessa Kerre; Tom Taghon; Georges Leclercq; Bart Vandekerckhove
Journal:  Int J Mol Sci       Date:  2020-11-20       Impact factor: 5.923

5.  Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate.

Authors:  Kazuyoshi Ishigaki; Soumya Raychaudhuri; Kaitlyn A Lagattuta; Joyce B Kang; Aparna Nathan; Kristen E Pauken; Anna Helena Jonsson; Deepak A Rao; Arlene H Sharpe
Journal:  Nat Immunol       Date:  2022-02-17       Impact factor: 31.250

6.  Complete Absence of CD3γ Protein Expression Is Responsible for Combined Immunodeficiency with Autoimmunity Rather than SCID.

Authors:  Ottavia M Delmonte; Jared H Rowe; Adam K Dobbs; Boaz Palterer; Riccardo Castagnoli; Luigi D Notarangelo
Journal:  J Clin Immunol       Date:  2020-11-19       Impact factor: 8.317

7.  Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2.

Authors:  Thomas Barthlott; Adam E Handel; Hong Ying Teh; Rushika C Wirasinha; Katrin Hafen; Saulius Žuklys; Benoit Roch; Stuart H Orkin; Jean-Pierre de Villartay; Stephen R Daley; Georg A Holländer
Journal:  Nat Commun       Date:  2021-06-24       Impact factor: 14.919

8.  Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.

Authors:  Rushika C Wirasinha; Ainsley R Davies; Monika Srivastava; Julie M Sheridan; Xavier Y X Sng; Ottavia M Delmonte; Kerry Dobbs; Khai L Loh; Lisa A Miosge; Cindy Eunhee Lee; Rochna Chand; Anna Chan; Jin Yan Yap; Michael D Keller; Karin Chen; Jamie Rossjohn; Nicole L La Gruta; Carola G Vinuesa; Hugh H Reid; Michail S Lionakis; Luigi D Notarangelo; Daniel H D Gray; Christopher C Goodnow; Matthew C Cook; Stephen R Daley
Journal:  J Exp Med       Date:  2021-02-01       Impact factor: 14.307

9.  Update in Primary Immunodeficiencies.

Authors:  Lucia Leonardi; Beatrice Rivalta; Caterina Cancrini; Elena Chiappini; Claudio Cravidi; Carlo Caffarelli; Sara Manti; Mauro Calvani; Alberto Martelli; Michele Miraglia Del Giudice; Marzia Duse; Gian Luigi Marseglia; Fabio Cardinale
Journal:  Acta Biomed       Date:  2020-09-15

10.  WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice.

Authors:  Wenyan Li; Yanjun Jia; Yanping Wang; Qin Zhao; Lu Yang; Ting Zeng; Linlin Niu; Rongxin Dai; Yanan Li; Xiaodong Zhao; Junfeng Wu
Journal:  Front Immunol       Date:  2022-01-18       Impact factor: 7.561
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