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Literature DB >> 31053335

Commitment Isn't for Everyone.

Abstract

The majority of malaria parasites during human infection are asexual and are unable to be transmitted to mosquitoes. Only sexually differentiated parasites (gametocytes) can be successfully transmitted to complete the lifecycle. In a recent study by Bancells et al. (Nat. Microbiol. 2019;4:144-154), a new route of sexual conversion is identified that does not require a prior round of replication.

Entities: Disease Gene Species

Keywords: Plasmodium falciparum; commitment; gametocyte; malaria; sexual stage

Mesh：

Year: 2019 PMID： 31053335 PMCID： PMC7163921 DOI： 10.1016/j.pt.2019.03.012

Source DB: PubMed Journal: Trends Parasitol ISSN： 1471-4922

11 in total

1. Commitment of the malaria parasite Plasmodium falciparum to sexual and asexual development.

Authors: M C Bruce; P Alano; S Duthie; R Carter
Journal: Parasitology Date: 1990-04 Impact factor: 3.234

2. Heterochromatin protein 1 secures survival and transmission of malaria parasites.

Authors: Nicolas M B Brancucci; Nicole L Bertschi; Lei Zhu; Igor Niederwieser; Wai Hoe Chin; Rahel Wampfler; Céline Freymond; Matthias Rottmann; Ingrid Felger; Zbynek Bozdech; Till S Voss
Journal: Cell Host Microbe Date: 2014-08-13 Impact factor: 21.023

3. A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion.

Authors: Bradley I Coleman; Kristen M Skillman; Rays H Y Jiang; Lauren M Childs; Lindsey M Altenhofen; Markus Ganter; Yvette Leung; Ilana Goldowitz; Björn F C Kafsack; Matthias Marti; Manuel Llinás; Caroline O Buckee; Manoj T Duraisingh
Journal: Cell Host Microbe Date: 2014-08-13 Impact factor: 21.023

4. Commitment to sexual differentiation in the human malaria parasite, Plasmodium falciparum.

Authors: T G Smith; P Lourenço; R Carter; D Walliker; L C Ranford-Cartwright
Journal: Parasitology Date: 2000-08 Impact factor: 3.234

5. Commitment to the production of male and female gametocytes in the human malaria parasite Plasmodium falciparum.

Authors: F Silvestrini; P Alano; J L Williams
Journal: Parasitology Date: 2000-11 Impact factor: 3.234

6. GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing.

Authors: Michael Filarsky; Sabine A Fraschka; Igor Niederwieser; Nicolas M B Brancucci; Eilidh Carrington; Elvira Carrió; Suzette Moes; Paul Jenoe; Richárd Bártfai; Till S Voss
Journal: Science Date: 2018-03-16 Impact factor: 47.728

7. Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum.

Authors: Cristina Bancells; Oriol Llorà-Batlle; Asaf Poran; Christopher Nötzel; Núria Rovira-Graells; Olivier Elemento; Björn F C Kafsack; Alfred Cortés
Journal: Nat Microbiol Date: 2018-11-26 Impact factor: 17.745

8. Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei.

Authors: Robyn S Kent; Katarzyna K Modrzynska; Rachael Cameron; Nisha Philip; Oliver Billker; Andrew P Waters
Journal: Nat Microbiol Date: 2018-09-03 Impact factor: 17.745

9. A transcriptional switch underlies commitment to sexual development in malaria parasites.

Authors: Björn F C Kafsack; Núria Rovira-Graells; Taane G Clark; Cristina Bancells; Valerie M Crowley; Susana G Campino; April E Williams; Laura G Drought; Dominic P Kwiatkowski; David A Baker; Alfred Cortés; Manuel Llinás
Journal: Nature Date: 2014-02-23 Impact factor: 49.962

10. A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.

Authors: Abhinav Sinha; Katie R Hughes; Katarzyna K Modrzynska; Thomas D Otto; Claudia Pfander; Nicholas J Dickens; Agnieszka A Religa; Ellen Bushell; Anne L Graham; Rachael Cameron; Bjorn F C Kafsack; April E Williams; Manuel Llinas; Matthew Berriman; Oliver Billker; Andrew P Waters
Journal: Nature Date: 2014-02-23 Impact factor: 49.962

1 in total

1. Antimalarial Natural Products.

Authors: David G I Kingston; Maria Belen Cassera
Journal: Prog Chem Org Nat Prod Date: 2022

1 in total