Literature DB >> 31051127

Beyond Purple Hearts: A Colorful Approach to Isolate Distinct Heart Cells from Human iPSCs.

Lauren N Randolph1, Xiaojun Lance Lian2.   

Abstract

In this issue of Cell Stem Cell, Zhang et al. (2019) describe a double-reporter iPSC line based on the expression of key cardiac transcription factors, TBX5 and NKX2.5, that delineates cardiac lineage specification in vitro and enables isolation of relatively pure chamber-specific cardiomyocytes, which are critical for drug screening, tissue engineering, and disease modeling.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2019        PMID： 31051127      PMCID： PMC7065719          DOI： 10.1016/j.stem.2019.04.003

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  10 in total

1.  Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations.

Authors:  Jee Hoon Lee; Stephanie I Protze; Zachary Laksman; Peter H Backx; Gordon M Keller
Journal:  Cell Stem Cell       Date:  2017-08-03       Impact factor: 24.633

2.  Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling.

Authors:  Xiaojun Lian; Cheston Hsiao; Gisela Wilson; Kexian Zhu; Laurie B Hazeltine; Samira M Azarin; Kunil K Raval; Jianhua Zhang; Timothy J Kamp; Sean P Palecek
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-29       Impact factor: 11.205

3.  A myocardial lineage derives from Tbx18 epicardial cells.

Authors:  Chen-Leng Cai; Jody C Martin; Yunfu Sun; Li Cui; Lianchun Wang; Kunfu Ouyang; Lei Yang; Lei Bu; Xingqun Liang; Xiaoxue Zhang; William B Stallcup; Christopher P Denton; Andrew McCulloch; Ju Chen; Sylvia M Evans
Journal:  Nature       Date:  2008-05-14       Impact factor: 49.962

Review 4.  Building the mammalian heart from two sources of myocardial cells.

Authors:  Margaret Buckingham; Sigolène Meilhac; Stéphane Zaffran
Journal:  Nat Rev Genet       Date:  2005-11       Impact factor: 53.242

5.  Generation of functional ventricular heart muscle from mouse ventricular progenitor cells.

Authors:  Ibrahim J Domian; Murali Chiravuri; Peter van der Meer; Adam W Feinberg; Xi Shi; Ying Shao; Sean M Wu; Kevin Kit Parker; Kenneth R Chien
Journal:  Science       Date:  2009-10-16       Impact factor: 47.728

6.  Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart.

Authors:  Sandra Puskaric; Stefanie Schmitteckert; Alessandro D Mori; Anne Glaser; Katja U Schneider; Benoit G Bruneau; Rüdiger J Blaschke; Herbert Steinbeisser; Gudrun Rappold
Journal:  Hum Mol Genet       Date:  2010-09-21       Impact factor: 6.150

7.  Embryonic stem cell lines derived from human blastocysts.

Authors:  J A Thomson; J Itskovitz-Eldor; S S Shapiro; M A Waknitz; J J Swiergiel; V S Marshall; J M Jones
Journal:  Science       Date:  1998-11-06       Impact factor: 47.728

8.  A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling.

Authors:  Yimu Zhao; Naimeh Rafatian; Nicole T Feric; Brian J Cox; Roozbeh Aschar-Sobbi; Erika Yan Wang; Praful Aggarwal; Boyang Zhang; Genevieve Conant; Kacey Ronaldson-Bouchard; Aric Pahnke; Stephanie Protze; Jee Hoon Lee; Locke Davenport Huyer; Danica Jekic; Anastasia Wickeler; Hani E Naguib; Gordon M Keller; Gordana Vunjak-Novakovic; Ulrich Broeckel; Peter H Backx; Milica Radisic
Journal:  Cell       Date:  2019-01-24       Impact factor: 41.582

9.  A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles.

Authors:  Joe Z Zhang; Vittavat Termglinchan; Ning-Yi Shao; Ilanit Itzhaki; Chun Liu; Ning Ma; Lei Tian; Vicky Y Wang; Alex C Y Chang; Hongchao Guo; Tomoya Kitani; Haodi Wu; Chi Keung Lam; Kazuki Kodo; Nazish Sayed; Helen M Blau; Joseph C Wu
Journal:  Cell Stem Cell       Date:  2019-03-14       Impact factor: 24.633

10.  Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions.

Authors:  Xiaoping Bao; Xiaojun Lian; Timothy A Hacker; Eric G Schmuck; Tongcheng Qian; Vijesh J Bhute; Tianxiao Han; Mengxuan Shi; Lauren Drowley; Alleyn Plowright; Qing-Dong Wang; Marie-Jose Goumans; Sean P Palecek
Journal:  Nat Biomed Eng       Date:  2016-12-05       Impact factor: 25.671
  10 in total
  1 in total

1.  Expression dynamics of HAND1/2 in in vitro human cardiomyocyte differentiation.

Authors:  Chikako Okubo; Megumi Narita; Azusa Inagaki; Misato Nishikawa; Akitsu Hotta; Shinya Yamanaka; Yoshinori Yoshida
Journal:  Stem Cell Reports       Date:  2021-07-22       Impact factor: 7.765
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.