Literature DB >> 31051126

Transcription Factor Stoichiometry Drives Cell Fate: Single-Cell Proteomics to the Rescue.

Thomas Graf1.   

Abstract

In this issue of Cell Stem Cell, Palii et al. (2019) use a proteomics approach to investigate the differentiation along the erythroid lineage of human hematopoietic progenitors. They show that antagonistic transcription factor pairs are co-expressed in single progenitors, refuting earlier claims, and that differentiation proceeds along a continuum of cell states.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31051126     DOI: 10.1016/j.stem.2019.03.002

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  4 in total

Review 1.  The quest of cell surface markers for stem cell therapy.

Authors:  Anna Meyfour; Sara Pahlavan; Mehdi Mirzaei; Jeroen Krijgsveld; Hossein Baharvand; Ghasem Hosseini Salekdeh
Journal:  Cell Mol Life Sci       Date:  2020-07-24       Impact factor: 9.261

Review 2.  Generation and clinical potential of functional T lymphocytes from gene-edited pluripotent stem cells.

Authors:  Rongqun Guo; Wei Li; Yadan Li; Yingmei Li; Zhongxing Jiang; Yongping Song
Journal:  Exp Hematol Oncol       Date:  2022-05-14

Review 3.  Single-cell fate decisions of bipotential hematopoietic progenitors.

Authors:  Marjorie Brand; Edward Morrissey
Journal:  Curr Opin Hematol       Date:  2020-07       Impact factor: 3.218

4.  Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination.

Authors:  Roman Zug
Journal:  Biol Open       Date:  2022-01-28       Impact factor: 2.422

  4 in total

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