Dan Li1,2, Shi-Bin Lin2, Biao Cheng1,3. 1. 1 Department of Plastic Surgery, Southern Medical University, Tong he Guangzhou, Guangdong, China. 2. 2 Department of Ophthalmology, Joint Shantou International Eye Center of Shantou University and Chinese University of Hong Kong, Shantou, Guangdong, China. 3. 3 Department of Plastic Surgery, General Hospital of Guangzhou Military Command of the PLA, Guangzhou, Guangdong, China.
Abstract
Background and objective: Several cases of meibomian gland dysfunction (MGD), particularly the moderate to severe ones, are considered intractable by traditional therapy. Intense pulsed light (IPL) therapy has emerged as a new choice for management of MGD in recent years, given that use of lasers and optical treatments is typically challenging in patients with darker skin types. Methods:IPL treatment for MGD is administered in the periorbital area with the thinnest skin in our body, which has an inherent risk of skin side effects. We evaluated the effects and safety of this therapy in Chinese patients with Fitzpatrick skin types III-IV. Forty MGD patients were randomly administered IPL treatment with two types of parameters in the left and the right eye. Results: Results revealed that both parameter settings of IPL treatment could gradually and effectively raise the tear breakup time (BUT) and ocular surface disease index (OSDI) score. However, younger patients showed better improvement in BUT (F = 19.54, p < 0.01) and OSDI (F = 9.93, p < 0.01) compared with older patients. Conclusions: Overall, results showed that IPL treatment is safe and effective in MGD patients with skin types III-IV.
RCT Entities:
Background and objective: Several cases of meibomian gland dysfunction (MGD), particularly the moderate to severe ones, are considered intractable by traditional therapy. Intense pulsed light (IPL) therapy has emerged as a new choice for management of MGD in recent years, given that use of lasers and optical treatments is typically challenging in patients with darker skin types. Methods: IPL treatment for MGD is administered in the periorbital area with the thinnest skin in our body, which has an inherent risk of skin side effects. We evaluated the effects and safety of this therapy in Chinese patients with Fitzpatrick skin types III-IV. Forty MGD patients were randomly administered IPL treatment with two types of parameters in the left and the right eye. Results: Results revealed that both parameter settings of IPL treatment could gradually and effectively raise the tear breakup time (BUT) and ocular surface disease index (OSDI) score. However, younger patients showed better improvement in BUT (F = 19.54, p < 0.01) and OSDI (F = 9.93, p < 0.01) compared with older patients. Conclusions: Overall, results showed that IPL treatment is safe and effective in MGD patients with skin types III-IV.