Literature DB >> 3104951

Fluoxetine suppresses palatability-induced ingestion.

J D Leander.   

Abstract

Non-deprived rats were allowed 1-h access to a range of saccharin solutions from 0.001 to 0.1 M Na saccharin. Compared to a group of rats drinking tap water, the rats drinking the saccharin solutions ingested a great deal more fluid, with as much as 24-30 ml consumed of the 0.01 M concentration, compared to 3-5 ml in controls. Fluoxetine (IP) decreased this palatability-induced excessive consumption in a dose-related manner. Effects of 10 mg/kg fluoxetine were apparent for 48 h after injection. This effect on palatability-induced ingestion may relate to previously reported effects of fluoxetine on food consumption.

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Year:  1987        PMID: 3104951     DOI: 10.1007/bf00518178

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  21 in total

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Authors:  J J Wurtman; R J Wurtman
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2.  Inhibition of drug-induced anorexia in rats by methysergide.

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3.  Palatability and body fluid homeostasis.

Authors:  B J Rolls; R J Wood; R M Stevens
Journal:  Physiol Behav       Date:  1978-01

4.  Evidence for a difference in mechanism of action between fenfluramine- and amphetamine-induced anorexia.

Authors:  S Jespersen; J Scheel-Krüger
Journal:  J Pharm Pharmacol       Date:  1973-01       Impact factor: 3.765

5.  Peripherally administered serotonin decreases food intake in rats.

Authors:  J D Pollock; N Rowland
Journal:  Pharmacol Biochem Behav       Date:  1981-08       Impact factor: 3.533

6.  Effect of 3-(p-trifluoromethylphenoxy). N. N. methyl-3-phenylpropylamine on the depletion of brain serotonin by 4-chloroamphetamine.

Authors:  R W Fuller; K W Perry; B B Molloy
Journal:  J Pharmacol Exp Ther       Date:  1975-06       Impact factor: 4.030

7.  Effects of manipulations of peripheral serotonin on feeding and drinking in the rat.

Authors:  P J Fletcher; M J Burton
Journal:  Pharmacol Biochem Behav       Date:  1984-06       Impact factor: 3.533

Review 8.  Is there a role for serotonin (5-hydroxytryptamine) in feeding?

Authors:  J E Blundell
Journal:  Int J Obes       Date:  1977

9.  Chlorophenylpiperazine: a central serotonin agonist causing powerful anorexia in rats.

Authors:  R Samanin; T Mennini; A Ferraris; C Bendotti; F Borsini; S Garattini
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-08       Impact factor: 3.000

10.  Fluoxetine and two other serotonin uptake inhibitors without affinity for neuronal receptors.

Authors:  D T Wong; F P Bymaster; L R Reid; P G Threlkeld
Journal:  Biochem Pharmacol       Date:  1983-04-01       Impact factor: 5.858

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  6 in total

1.  Effects of chronically administered fluoxetine and fenfluramine on food intake, body weight and the behavioural satiety sequence.

Authors:  J McGuirk; R Muscat; P Willner
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

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4.  Effect of hypothalamic and peripheral fluoxetine injection on natural patterns of macronutrient intake in the rat.

Authors:  G F Weiss; N Rogacki; A Fueg; D Buchen; J S Suh; D T Wong; S F Leibowitz
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

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Authors:  Bankole A Johnson
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6.  Depression after status epilepticus: behavioural and biochemical deficits and effects of fluoxetine.

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  6 in total

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