Samera Ahmad1, Daniel Capiz-Correa1, Hans E Grossniklaus1,2. 1. Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA. 2. Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA.
Abstract
AIM: To describe the clinicopathologic features of pyogenic granuloma (granulation tissue proliferation) extending from the retina. METHODS: We describe 3 patients who underwent enucleation for endophthalmitis. The eyes were processed routinely for histopathologic examination. RESULTS: All 3 enucleated eyes contained granulation tissue with reactive vascular channels and intervening stroma infiltrated with inflammatory cells. The vascular channels were arranged in a fan-like configuration and the tissue was classified as representing pyogenic granulomas. CONCLUSIONS: Pyogenic granulomas (granulation tissue) may emanate from the retina in cases of endophthalmitis. This is distinct from neovascularization that may occur in proliferative diabetic retinopathy, central retinal vein occlusion, or other etiologies.
AIM: To describe the clinicopathologic features of pyogenic granuloma (granulation tissue proliferation) extending from the retina. METHODS: We describe 3 patients who underwent enucleation for endophthalmitis. The eyes were processed routinely for histopathologic examination. RESULTS: All 3 enucleated eyes contained granulation tissue with reactive vascular channels and intervening stroma infiltrated with inflammatory cells. The vascular channels were arranged in a fan-like configuration and the tissue was classified as representing pyogenic granulomas. CONCLUSIONS: Pyogenic granulomas (granulation tissue) may emanate from the retina in cases of endophthalmitis. This is distinct from neovascularization that may occur in proliferative diabetic retinopathy, central retinal vein occlusion, or other etiologies.
Authors: R Bragado; E Bello; L Requena; G Renedo; E Texeiro; M V Alvarez; M A Castilla; C Caramelo Journal: Acta Derm Venereol Date: 1999-11 Impact factor: 4.437
Authors: Hyung Cho; Ahmad A Alwassia; Caio V Regiatieri; Jason Y Zhang; Caroline Baumal; Nadia Waheed; Jay S Duker Journal: Retina Date: 2013-03 Impact factor: 4.256