Kazuomi Kario1, Jose Ramon Rumoroso2, Yukie Okawara1, Armando Pérez de Prado3, Eulogio Garcia Fernandez4, Hideaki Kagitani5, Francisco Javier Goicolea Gómez6, Oriol Rodríguez Leor7, Goran Stankovic8. 1. Department of Cardiovascular Medicine, Jichi Medical University School of Medicine, Tochigi, Japan. 2. Interventional Cardiology Department, Hospital Galdakao, Bilbao, Spain. 3. Department of Cardiology, Hospital de Léon, Léon, Spain. 4. Department Interventional Cardiology, Hospital Monteprincipe, Madrid, Spain. 5. Terumo Corporation, Tokyo, Japan. 6. Interventional Cardiology Unit, Hospital Puerta de Hierro/Majadahonda, Madrid, Spain. 7. Interventional Cardiology Unit, Hospital Germans Trias I Pujol, Barcelona, Spain. 8. Department of Cardiology, Clinical Center of Serbia, Belgrade, Serbia.
Abstract
BACKGROUND/AIMS: We assessed the feasibility of renal sympathetic denervation (RDN) treatment in patients with resistant hypertension using the Iberis® RDN system. This study was a prospective, multicenter, single-arm feasibility registry. METHODS: We collected data from patients who underwent RDN treatment using the Iberis system. From November 2014 to February 2016, 16 patients from 6 centers in Europe were enrolled in this registry. RESULTS: Consistent reductions in the 24-h systolic blood pressure (SBP) and diastolic blood pressure were obtained. At any follow-up point, more than 70% of the patients were responders. The change in the 24-h SBP at 1 month was strongly correlated with that at 12 months. CONCLUSION: The Iberis system is safe and effective in patients for the treatment of resistant hypertension. Furthermore, our results suggest that we can estimate the effect of RDN in the long term at the 1-month follow-up point using the 24-h SBP.
BACKGROUND/AIMS: We assessed the feasibility of renal sympathetic denervation (RDN) treatment in patients with resistant hypertension using the Iberis® RDN system. This study was a prospective, multicenter, single-arm feasibility registry. METHODS: We collected data from patients who underwent RDN treatment using the Iberis system. From November 2014 to February 2016, 16 patients from 6 centers in Europe were enrolled in this registry. RESULTS: Consistent reductions in the 24-h systolic blood pressure (SBP) and diastolic blood pressure were obtained. At any follow-up point, more than 70% of the patients were responders. The change in the 24-h SBP at 1 month was strongly correlated with that at 12 months. CONCLUSION: The Iberis system is safe and effective in patients for the treatment of resistant hypertension. Furthermore, our results suggest that we can estimate the effect of RDN in the long term at the 1-month follow-up point using the 24-h SBP.
Authors: Stacie L Daugherty; J David Powers; David J Magid; Heather M Tavel; Frederick A Masoudi; Karen L Margolis; Patrick J O'Connor; Joe V Selby; P Michael Ho Journal: Circulation Date: 2012-02-29 Impact factor: 29.690
Authors: Murray D Esler; Henry Krum; Paul A Sobotka; Markus P Schlaich; Roland E Schmieder; Michael Böhm Journal: Lancet Date: 2010-11-17 Impact factor: 79.321
Authors: Henry Krum; Markus P Schlaich; Paul A Sobotka; Michael Böhm; Felix Mahfoud; Krishna Rocha-Singh; Richard Katholi; Murray D Esler Journal: Lancet Date: 2013-11-07 Impact factor: 79.321
Authors: David A Calhoun; Daniel Jones; Stephen Textor; David C Goff; Timothy P Murphy; Robert D Toto; Anthony White; William C Cushman; William White; Domenic Sica; Keith Ferdinand; Thomas D Giles; Bonita Falkner; Robert M Carey Journal: Circulation Date: 2008-06-24 Impact factor: 29.690
Authors: Giuseppe Mansia; Guy De Backer; Anna Dominiczak; Renata Cifkova; Robert Fagard; Giuseppe Germano; Guido Grassi; Anthony M Heagerty; Sverre E Kjeldsen; Stephane Laurent; Krzysztof Narkiewicz; Luis Ruilope; Andrzej Rynkiewicz; Roland E Schmieder; Harry A Struijker Boudier; Alberto Zanchetti Journal: Blood Press Date: 2007 Impact factor: 2.835
Authors: Deepak L Bhatt; David E Kandzari; William W O'Neill; Ralph D'Agostino; John M Flack; Barry T Katzen; Martin B Leon; Minglei Liu; Laura Mauri; Manuela Negoita; Sidney A Cohen; Suzanne Oparil; Krishna Rocha-Singh; Raymond R Townsend; George L Bakris Journal: N Engl J Med Date: 2014-03-29 Impact factor: 91.245
Authors: Henry Krum; Markus Schlaich; Rob Whitbourn; Paul A Sobotka; Jerzy Sadowski; Krzysztof Bartus; Boguslaw Kapelak; Anthony Walton; Horst Sievert; Suku Thambar; William T Abraham; Murray Esler Journal: Lancet Date: 2009-03-28 Impact factor: 79.321